Pyrazolecarboxylic acid tricyclic derivatives, preparation...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S322000, C514S406000, C546S016000, C546S199000, C548S359500

Reexamination Certificate

active

06906080

ABSTRACT:
The subject of the invention is tricyclic derivatives of pyrazolecarboxylic acid of formula:in which R1represents a C3-C15carboxyl radical or an NR2R3group. The invention also relates to the method for preparing the compounds of formula (I), pharmaceutical compositions containing them. The compounds of formula (I) are active on cannabinoid CB1receptors.

REFERENCES:
patent: 3940418 (1976-02-01), Hamilton
patent: 5420141 (1995-05-01), Boigegrain et al.
patent: 5462960 (1995-10-01), Barth et al.
patent: 5624941 (1997-04-01), Barth et al.
patent: 6028084 (2000-02-01), Barth et al.
patent: 0477049 (1992-03-01), None
patent: 0568546 (1993-11-01), None
patent: 576357 (1993-12-01), None
patent: 0658546 (1994-12-01), None
patent: WO 96/09304 (1996-03-01), None
patent: WO 97/19063 (1997-05-01), None
Hamilton, R.W., Journal of Heterocyclic Chemistry, vol. 13, No. 3, pp. 545-553 (1976).
Fravolini, A. et al., Farmaco, Ed. Sci., vol. 33, No. 11, pp. 855-860 (1978).

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