Materials and methods for treating hypercholesterolemia

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S277000, C546S318000, C546S342000

Reexamination Certificate

active

06951877

ABSTRACT:
The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can be advantageously used to treat patients suffering hypercholesterolemia.

REFERENCES:
patent: 5849749 (1998-12-01), Fey et al.
patent: 0 464 817 (1992-01-01), None
patent: WO 01 81328 (2001-11-01), None
patent: WO 01 85975 (2001-11-01), None
patent: WO 02 24689 (2002-03-01), None

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