Nucleic acids encoding tumor necrosis factor receptor TR10

Details Nucleic acids encoding tumor necrosis factor receptor TR10 Nucleic acids encoding tumor necrosis factor receptor TR10

2005-11-29

2005-11-29

Kemmerer, Elizabeth (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C536S023500, C530S350000

Reexamination Certificate

active

06969599

ABSTRACT:
The present invention relates to a novel protein, TR10, which is a member of the tumor necrosis factor (TNF) receptor superfamily and the TRAIL receptor subfamily. In particular, isolated nucleic acid molecules are provided encoding the human TR10 protein. TR10 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of TR10 activity.

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