Tryptase inhibitors

Details Tryptase inhibitors Tryptase inhibitors

2005-11-08

2005-11-08

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S518000, C548S469000, C548S361100, C546S208000, C546S276400, C514S326000, C514S343000

Reexamination Certificate

active

06962941

ABSTRACT:
The compounds of formula Iin which M, B1, B2, R1, R2, R6, R7, K1 and K2 have the meanings as indicated in the description are novel active tryptase inhibitors.

REFERENCES:
patent: 6489327 (2002-12-01), Bär et al.
patent: 6613769 (2003-09-01), Bode et al.
patent: WO 95/32945 (1995-12-01), None
patent: WO 96/09297 (1996-03-01), None
patent: WO 98/04537 (1998-02-01), None
patent: WO99/12918 (1999-03-01), None
patent: WO 99/24395 (1999-05-01), None
patent: WO 99/24407 (1999-05-01), None
patent: WO 00/14097 (2000-03-01), None
patent: WO 01/10845 (2001-02-01), None
patent: WO 01/10848 (2001-02-01), None
patent: WO 01/19809 (2001-03-01), None
patent: WO 01/46128 (2001-06-01), None
patent: WO 01/46168 (2001-06-01), None
patent: WO 02/60895 (2002-08-01), None
patent: WO 02/66420 (2002-08-01), None
patent: WO 02/66430 (2002-08-01), None
patent: WO 02/74733 (2002-09-01), None
Krishna, et al., “Inhibition of mast cell tryptase by inhaled APC 366 attenuates allergen-induced late-phase airway obstruction in asthma”,J. Allergy Clin. Immunol., Jun., 2001, pp. 1039-1045.
Rice, et al., “Dibasic Inhibitors of human mast cell tryptase. Part 2: Structure-Activity Relationships and Requirements for Potent Activity”, Bioorganic & Medicinal Chemistry Letters 10, pp. 2361-2366 (2000).

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