Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the...

Details Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the... Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the...

2005-08-23

2005-08-23

Shameem, Golam M M (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

C548S406000, C548S530000, C546S184000, C546S248000, C549S356000, C549S357000, C549S369000, C549S375000

Reexamination Certificate

active

06933385

ABSTRACT:
The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.

REFERENCES:
patent: WO 00/58254 (2000-10-01), None
Taylor et al., “Total Synthesis of Epothilones B and D,”Organic Letters, vol. 3, No. 14, 2001, pp. 2221-2224.
Fürstner et al., “Concise Total Syntheses of Epothilone A and C Based on Alkyne Metathesis,”Chem. Commun., 2001, pp. 1057-1059.
Mulzer et al., “Total Syntheses of Epothilones B and D,”J. Org. Chem., vol. 65, No. 22, 2000, pp. 7456-7467.

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