Preparation of a hepatitis B immune globulin and use thereof as

Details Preparation of a hepatitis B immune globulin and use thereof as Preparation of a hepatitis B immune globulin and use thereof as

1975-07-28

1977-05-03

Gotts, Lewis

Drug, bio-affecting and body treating compositions

Lymphokine

424 12, 260112R, 260112B, A61K 3942

Patent

active

040215407

ABSTRACT:
A method for producing a novel immunizing agent is described. The immunizing agent is anti-HB.sub.s gamma globulin essentially free of fibrinogen, plasminogen, 19 S globulin and lipids found to be effective in immunizing against hepatitis B virus disease. The method of producing this material involves fractionation of human plasma utilizing selective solvent and control of pH, temperature and ionic strength.

REFERENCES:
tullis, "Blood Cells & Plasma Proteins", Academic Press Inc., NY, 1953, pp. 21,30.

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