Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2005-06-07
2005-06-07
Woitach, Joseph T. (Department: 1632)
Chemistry: molecular biology and microbiology
Vector, per se
C435S325000, C435S366000, C435S372300, C435S455000, C424S093200
Reexamination Certificate
active
06902929
ABSTRACT:
The invention relates to the production and use of retroviral vectors for cell specific gene transfer, specially to a production method of retroviral vectors containing capsid particles of murine leukemia virus (MLV) and envelope proteins of human immunodeficiency vises (HIV) or simian immunodeficiency viruses (SIV). Said vectors can be used for gene transfer in selected cell types, specially in CD4-positive mammal cells.
REFERENCES:
patent: WO 96/17071 (1996-06-01), None
patent: WO 96/30533 (1996-10-01), None
patent: WO 98/38325 (1998-09-01), None
Schnierle et al., “Pseudotyping of murine leukemia virus with the envelope glycoproteins fo HIV generates a retroviral vector with specificity of infection for CD4-expressing cells”, Proc. Natl. Acad. Sci. USA, 94:8640-8645, Aug. 1997.
Mammano et al., “Truncation to the human immunodeficiency virus type 1 envelope glycoprotein allows efficient pseudotyping of Moloney murine leukemia virus particles and gene transfer into CD4+ cells”, J. Virol., 71:3341-3345, Apr. 1997.
Parolin et al., “Analysis in human immunodeficiency virus type 1 vectors of cis-acting sequences that affect gene transfer into human lymphocytes”, J. Virol., 68:3888-3895, Jun. 1994.
Salmons et al., “Construction of retroviral vectors for targeted delivery and expression of therapeutic genes”, Leukemia, 9(Suppl.):S53-S60, Oct. 1995.
Wilk et al., “Retained infectivity and cytopathogenicity of HIV-1 despite truncation of the C-terminal tail of the env gene product”, Virology, 189:167-177, Jul. 1992.
Denesvre et al., “TM domain swapping of murine leukemia virus and human T-cell leukemia virus envelopes confers different infectious abilities despite similar incorporation into virions”, J. Virol., 70:4380-4386, Jul. 1996.
Zingler and Littman, “Truncation fo the cytoplasmic domain of the simian immunodeficiency virus envelope increases env incorporation into particles and fusogenicity and infectivity”, J. Virol., 67:2824-2831, May 1993.
Anderson, “Human gene therapy”, Nature, 392(Suppl.):25-30, Apr. 1998.
Verma and Somia, “Gene therapy-promises, problems and prospects”, Nature, 389:239-242, Sep. 1997.
Hohne, “Truncation of the human immunodeficiency virus-type-2 envelope glycoprotein allows efficient pseudotyping of murine leukemia virus retroviral vector particles”, Virology, 261(1):70-78, Aug. 1999.
Chemical Abstracts, 125:785060b, (1996).
Cosset et al., “High-Titer Packaging . . . Human Serum”,Journal of Virology, 12:7430-7435, (1995).
Mammano et al., “Truncation of the Human Imunodeficiency . . . into CD4+ Cells”,Journal of Virology, 71:3341-3345, (1997).
Miller et al., “Targeted Vectors for Gene Therapy”,The FASEB Journal, 9:190-199, (1995).
Salmons et al., “Construction of Retroviral Vectors . . . Therapeutic Genes”,Lukemia, 9:S53-S60, (1995).
Takeuchi et al., “Retroviral Pseduotypes . . . Not D-type Retroviruses”,Virology, 186:792-794 (1992).
Schnierle et al., “Pseudotyping of Murine . . . CD4-expressing cells”,Proc. Natl. Acad. Sci., 94:8640-8645, (1997).
von Kalle et al., “Increased Gene Transfer . . . Retroviral Vector”, Blood, 84:2890-2897, (1994).
T. Wilk et al., “Retained in Vitro Infectivity and Cytopathogenicity of HIV-1 Despite Truncation of the C-Terminal Tail of the env Gene Product”,Virology, 189:167-177: (1992).
C. Wilson et al., “Formation of Infectious Hybrid Virions. . . of Moloney Murine Lukemia Virus”,Journal of Virology, 63(5):2374-2378, (1989).
Cichutek Klaus
Stitz Jorn
Bundesrepublik Deutschland last Represented by the President of
Woitach Joseph T.
LandOfFree
Retroviral vectors, methods for their preparation and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Retroviral vectors, methods for their preparation and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Retroviral vectors, methods for their preparation and their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3459864