Fluorescence detection with increased dynamic range

Details Fluorescence detection with increased dynamic range Fluorescence detection with increased dynamic range

2005-10-04

2005-10-04

Allen, Stephone B. (Department: 2878)

Radiant energy

Photocells; circuits and apparatus

Optical or pre-photocell system

C356S318000, C356S417000

Reexamination Certificate

active

06952008

ABSTRACT:
The light detection system includes at least two light detection elements. Each element is responsive to a selected light color in a first mode, and each element has a different sensitivity and is responsive to a single color in a second mode for enhanced dynamic range. A preferred embodiment includes four light detectors for responding to four separate colors or for responding with enhanced dynamic range to two colors. Embodiments are disclosed using a mirror/beam splitter arrangement to switch between modes and an embodiment including dichroic filters serving as fractional beam splitters.

REFERENCES:
patent: 6141096 (2000-10-01), Stern et al.

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