Method of identifying modulators of HIV-1 Vpu and Gag...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S152100, C424S172100, C424S185100, C435S339100, C530S350000

Reexamination Certificate

active

06927023

ABSTRACT:
A preparation of U binding protein (Ubp) and a gene sequence encoding Ubp and an anti-Ubp antibody are disclosed. An assay to identify modulators of Ubp/Vpu interaction and Gag/Ubp interaction is also disclosed.

REFERENCES:
S. Bour, et al., “The-Human Immunodeficiency Virus Type 1 Vpu Protein Specifically Binds to the Cytoplasmic Domain of CD4: Implications for a Mechanism of Degradation” J Virol 69:1510-1520 1995.
M.A. Callahan, et al., “Functional Interaction of Human Immunodeficiency Virus Type 1 Vpu and Gag with a Novel Member of the Tetratricopeptide Repeat Protein Family,” J. Virol 72(6):5189-5197 1998.
R.J. Geraghty, et al., “Cell Type-dependence for Vpu Function,” J. Med. Primatol. 23:146-150, 1994.
Y.-H. Lee, et al., “The HIV-1 Matrix Domain of Gag is Required for Vpu Respnsiveness During Particle Release,” Virology 237:46-55, 1997.
M.S. McBride, et al., “Position Dependence of Functional Hairpins Important for Human Immunodeficiency Virus Type 1 RNA Encapsidation In Vivo,” J. Virol. 71(3):2050-2058, 1997.
M.S. McBride, et al., “Efficient Encapsidation of Human Immunodeficiency Virus Type 1 Vectors and Further Characterization of cis Elements Required for Encapsidation,” Journal of Virology 71(6):4544-4554 1997.
M.D. Schwartz, et al., “Distinct Functions and Requirements for the Cys-His Boxes of the Human Immunodeficiency Virus Type 1 Nucleocapsid Protein during RNA Encapsidation and Replication.” J. Virol. 71(12):9295-9305. 1997.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of identifying modulators of HIV-1 Vpu and Gag... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of identifying modulators of HIV-1 Vpu and Gag..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of identifying modulators of HIV-1 Vpu and Gag... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3451985

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.