Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-10-18
2005-10-18
Schwadron, Ronald B. (Department: 1644)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S069600, C435S069100
Reexamination Certificate
active
06955900
ABSTRACT:
The present invention describes methods for producing binding sites on polypeptides, and particularly for producing binding sites within the CDR regions of immunoglobulin heavy or light chains that are displayed on the surface of filamentous phage particles. The invention also describes oligonucleotides useful for preparing the binding sites, and human monoclonal antibodies produced by the present methods.
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Barbas, III Carlos F.
Lerner Richard A.
Fitting Thomas
McCarthy Michael J.
Schwadron Ronald B.
The Scripps Research Institute
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