Inhibitor and preservative formulation

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...

Reexamination Certificate

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Reexamination Certificate

active

06875452

ABSTRACT:
The present invention provides an inhibitor and preservative formulation comprising a combination of a plant oil chosen from the oils of fennel, anise or basic, or derivatives or active ingredients thereof with benzoic acid, methyl paraben, ethyl paraben, propyl paraben or butyl paraben. Suitably the formulation comprises between 0.1% and 1% of plant oil derivative or active ingredient thereof and 0.1% benzoic acid or paraben. The ingredients may be administered separately or together to a foodstuff. Alternatively the ingredients may be used in the manufacture of medicament to inhibit micro-organism growth.

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Fyfe et al. Inhibition ofListeria monocytogenesandSalmonella enteriditisby Combinations of Plant Oils and Derivatives of Benzoic Acid: The Development of Synergistic Antimicrobial Combinations; Int. Journal of Antimicrobial Agents 9 (1998) pp. 195-199.*
Fyfe, L., et al. (abstract). (1997). Inhibition ofListeria monocytogenesandSalmonella enteriditisby Combinations of Plant Oils and Derivatives of Benzoic Acid: The Development of synergistic Antimicrobial Combinations.Int J Antimicrob Agents.9(3): 195-199.
Hodgson, I., et al. (abstract). (1998). Inhibition of Bacteria and Yeast by Oil of Fennel and Paraban: Development of Synergistic Antimicrobial Combinations.Journal of Essential Oil Research.78:1216-1220.
Lachowicz, K.J., et al. (abstract). (1998). The Synergistic Preservative Effects of the Essential Oils of Sweet Basil (ocimum basilicum L.) Against Acid-Tolerant Food Microflora.Letters in Applied Microbiology. 26(3):209-214.
Wan, J., et al. (abstract). (1998). The Effect of Essential Oils of Basil on the Growth of Aeromonas Hydrophilia and Pseudomonas Fluorescens.Journal of Applied Microbiology.84(2):152-158.
El-Gengaihi, S., et al. (abstract). (1982). Biological Investigation of Some Essential Oils Isolated from Egyptian Plants.Pharm. Sci. Lab. Natl. Res. Cent.21(1):107-111.
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Arora, R., et al. (abstract). (1984). Application of Essential Oils and Their Isolates as Preservative of Citrus-Reticulata.Biol. Mem.9(1):98-104.

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