Substituted benzimidazoles, processes for their preparation,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S307400

Reexamination Certificate

active

06958357

ABSTRACT:
The invention relates to the use of compounds of formula I for the production of a medicament for the treatment of illnesses which can be influenced by inhibition of the Na+/H+ exchanger, and to a medicament comprising them.in which R1 to R9 have the meanings shown in the claims.

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patent: 98/08818 (1998-03-01), None
A.-M M. E. Omar, “The Cyclodesulfurization of Thio Compounds; VII. A New Facile Synthesis of Nα-Substituted Benzimidazoles,” pp 41-42 (1974).
T. Jen et al., “Amidines and Related Compounds. 6. Studies on Structure-Activity Relationships of Antihypertensive and Antisecretory Agents Related to Clonidine,”Journal of Medicinal Chemistry, vol. 18, No. 1:90-99 (1975).
Database Caplus, Chemical Abstracts Service, “Dependence of acute toxicity on structure in a series of 2-substituted benzimidazoles,”Med. Parazitol. Parazit. Bolezni44(3):316-322 (1975).
Meral Tunçbilek et al., “Synthesis and Antimicrobial Activity of Some New Anilino Benzimidazoles,”Arch. Pharm. Pharm. Med. Chem., 330:372-376 (1997).
Abstract of HU 9900625 (search for abstract at http://pipacsweb.hpo.hu/piaopt/pia04_09.htm?v=hunpia&a=start).

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