Microfluidic devices with thick-film electrochemical detection

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C204S451000, C204S455000, C204S601000, C204S603000, C204S605000, C435S006120

Reexamination Certificate

active

06878255

ABSTRACT:
An apparatus for conducting a microfluidic process and analysis, including at least one elongated microfluidic channel, fluidic transport means for transport of fluids through the microfluidic channel, and at least one thick-film electrode in fluidic connection with the outlet end of the microfluidic channel. The present invention includes an integrated on-chip combination reaction, separation and thick-film electrochemical detection microsystem, for use in detection of a wide range of analytes, and methods for the use thereof.

REFERENCES:
patent: 4908112 (1990-03-01), Pace
patent: 5846727 (1998-12-01), Soper et al.
patent: 5858195 (1999-01-01), Ramsey
patent: 5872010 (1999-02-01), Karger et al.
patent: 5904824 (1999-05-01), Oh
patent: 5906723 (1999-05-01), Mathies
patent: 6045676 (2000-04-01), Mathies et al.
patent: 6063259 (2000-05-01), Wang et al.
patent: 6068752 (2000-05-01), Dubrow et al.
patent: 6103199 (2000-08-01), Bjornson et al.
patent: 6110343 (2000-08-01), Ramsey et al.
patent: 6207031 (2001-03-01), Adourian et al.
patent: 6251343 (2001-06-01), Dubrow et al.
patent: 6274089 (2001-08-01), Chow et al.
patent: WO 9809161 (1998-03-01), None
Wang, J., et al., “Electrochemical Activation of Screen-Printed Carbon Strips,” Analyst, vol. 121, pp 345-350 (Mar. 1996).
Wang, J., et al., “Performance of Screen-Printed Carbon Electrodes Fabricated from Different Carbon Inks,” Electrochimica Acta, vol. 43, No. 23, pp 34359-3465 (1998).
Wang, J., et al., “Integrated Electrophoresis Chips/Amperomeric Detection with Sputtered Gold Working Electrodes,” Anal. Chem., vol. 71, No. 17, pp 3901-3904 (1999).
Wang, J., et al., “Capillary Electrophoresis Chips with Thick-Film Amperometric Detectors: Separation and Detection of Hydrazine Compounds,” Electroanalysis 2000, vol. 12, No. 9, pp 691-694 (1999).
Wang, J., et al., “Capillary Electrophoresis Chips with Thick-Film Amperometric Detectors: Separation and Detection of Phenolic Compounds,” Analytica Chimica Acta, vol. 416, pp 9-14 (2000).
Wang, J., et al., “Micromachined Electrophoresis Chips with Thick-Film Electrochemical Detectors,” Analytical Chem., vol. 71, No. 23, pp 5436-5440 (Dec. 1, 1999).
Wang, J., et al., “Microfabricated Electrophoresis Chips for Simultaneous Bioassays of Glucose, Uric Acid, Ascorbic Acid and Acetaminophen,” Analytical Chem., vol. 72, No. 11, pp 2514-2518 (Jun. 1, 2000).
Wang, J., Textbook “Analytical Electrochemistry” Wiley-VCH, A. John Wiley & Sons, Inc., New York, Second Edition (2000) copy of table of contents provided only.
Woolley, A.T., et al., “Capillary Electrophoresis Chips with Integrated Electrochemical Detection,” Anal. Chem., vol. 70, pp 684-688 (1998).
Zhong, M., t al., “Integrated On-Capillary Electrochemical Detector for Capillary Electrophoresis,” Anal. Chem., vol. 68, pp 2488-2493 (1996).
Curry Jr., P.D., et al., “Electrochemical Detection for Capillary Electrophoresis,” Electroanalysis, vol. 3, pp 587-596 (1991).
Freemantle, M., “Downsizing Chemistry,” C&EN pp 27-35 (Feb. 22, 1999).
Gavin, P.F., et al., “Characterization of Electrochemical array Detection for continuous Channel Electrophoretic Separations in Micrometer and Submicrometer Channels,” Anal. Chem., vol. 69, pp 3838-3845 (1997).
Gunasingham, H., et al., “Wall-Jet Eelctrode in Continuous Monitoring Voltammetry,” Anal. Chem. vol. 55, pp 1409-1414 (1983).
Hadd, A.G., et al., “Microchip Device for Performing Enzyme Assays,” Anal. Chem, vol. j6, pp 3407-3412 (1997).
Hart, J.P., et al., “Screen-Printed Voltammetric and Amperometric Electrochemical Sensors for Decentralized Testing,” Electroanalysis, vol. 6, pp 617-624 (1994).
Hilmi, A., et al., “Development of Electorkinetic Capillary Electrophoresis Equipped with Amprometric Detection for Analysis of Explosive Compounds,” Anal. Chem., vol. 71, pp 873-878 (1999).
Holland, L.A., et al., “Capillary Electrophoresis Coupled to Electrochemical Detection: A Review of Recent Advances,” Analytical Communications vol. 35, pp 1H-4H (Feb. 1998).
Kirk, Julienne K., et al., “Important Features of Blood Blucose Meters,” Journal of Amer. Pharm Assn, vol. 38, No. 2, PP 210-219 (Mar./Apr. 1998).
Kovacs, G.T.A., et al., “Silicon Micromachining Sensors to Systems” Anal. Chem., pp 407A-412A Jul. 1, 1996).
Rippeth, J.J., et al., “Flow-Injection Detector Incorporating a Screen-Printed Dispensable Amperometric Biosensor for Monitoring Organophosphate Pesticides,” Analyst, vol. 122, pp 1425-1429 (Nov. 1997).
Henry, C.S., et al., “Ceramic Microchips for Electrophoresis-Electrochemistry,”Anal. Commun., vol. 36, pp 305-307 (1999).
Hilmi, A., et al., “Electrochemical Detectors Prepared by Electroless Deposition for Microfabricated Electrophoresis Chips,”Analytical Chemistry, vol. 72, No. 19, pp 4577-4682 (Oct. 1, 2000).
Rossler, J.S., et al., “Microchannel Networks for Electrophoretic Separations,”Electrophoresis, vol. 20, pp 727-731 (1999).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Microfluidic devices with thick-film electrochemical detection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Microfluidic devices with thick-film electrochemical detection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Microfluidic devices with thick-film electrochemical detection will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3439145

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.