Pyrrolo[2,1-f][1,2,4]triazine inhibitors of kinases

Details Pyrrolo[2,1-f][1,2,4]triazine inhibitors of kinases Pyrrolo[2,1-f][1,2,4]triazine inhibitors of kinases

2005-03-22

2005-03-22

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S183000

Reexamination Certificate

active

06869952

ABSTRACT:
The present invention provides compounds of formula I,and pharmaceutically acceptable salts thereof.The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

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