Substituted urea retinoid agonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S378000, C514S438000, C514S585000, C514S586000, C514S535000, C514S564000, C514S567000, C514S596000, C514S598000, C514S534000, C514S423000, C514S562000, C514S317000, C546S306000, C546S205000, C548S247000, C548S530000, C549S077000, C560S034000, C560S016000, C562S439000, C564S026000, C564S034000, C564S048000, C564S049000, C564S163000

Reexamination Certificate

active

06838472

ABSTRACT:
The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and dermatological disorders and methods for delivering formulations into the lung of a mammal suffering from emphysema, cancer and dermatological disorders.

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Ebisawa, et al., “Novel Retinoidal Tropolone Derivatives. Bioisosteric Relationship of Tropolone Ring with Benzoic Acid Moiety in Retinoid Structure,”Chemical and Pharmaceutical Bulletin, (2001) pp 501-503, vol. 49:4.
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