Substituted imidazo [1,2-a] pyridine derivatives

Details Substituted imidazo [1,2-a] pyridine derivatives Substituted imidazo [1,2-a] pyridine derivatives

2005-03-01

2005-03-01

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S121000

Reexamination Certificate

active

06861437

ABSTRACT:
The present invention is a series of novel compounds of formula I and a method of treatment or prevention of a mGluR5 receptor mediated disease by administering an therapeutically effective amount of a compound formulawherein R1and R2are selected from hydrogen, (C1-6)-alkyl, halogen, hydroxy, (C1-6)-alkoxy and A is defined the description, or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3701780 (1972-10-01), Fisher
patent: 6596731 (2003-07-01), Mutel et al.
patent: 590 862 (1977-08-01), None
patent: 050 563 (1982-04-01), None
patent: 092 458 (1983-10-01), None
patent: 092 459 (1983-10-01), None
patent: 172 096 (1986-02-01), None
patent: 185 345 (1986-06-01), None
patent: 234 970 (1987-09-01), None
patent: 251 859 (1988-01-01), None
patent: 267 111 (1988-05-01), None
patent: 2 581 646 (1986-11-01), None
patent: 50-140477 (1975-11-01), None
patent: 51-004194 (1976-01-01), None
patent: 51-125095 (1976-10-01), None
patent: 11-116481 (1999-04-01), None
patent: WO 9119497 (1991-12-01), None
patent: WO 9839342 (1998-09-01), None
patent: WO 0008021 (2000-02-01), None
patent: WO 0174815 (2001-10-01), None
Schlaeger et al., Cytotechnology, 30, pp. 71-83 (1999).
Möhler et al., Nature, 294, pp. 763-765 (1981).
Katritzky et al., J. Org. Chem., 65, pp. 9201-9205 (2000).
Sundberg et al., J. Heterocyclic Chem., 25, pp. 129-137 (1988).
Andreani et al., Eur. J. Med. Chem., 29, pp. 339-342 (1994).
Habermann et al., J. Chem. Soc., Perkin Trans. 1, pp. 2425-2427 (1999).
Arbilla et al., Eur. J. Pharmacol., 130, pp. 257-263 (1986).
Maruyama et al., Arzneim.-Forsch, 31(7), pp. 1111-1118 (1981).
Crestani et al., Br. J. Pharmacol, 131, pp. 1251-1254 (2000).
Buu-Hoï et al., J. Org. Chem., 19, pp. 1370-1374 (1954).
Buu-Hoï et al., Recl. Trav. Chim. Pays-Bas, 68, pp. 441-472 (1949).
Möhler et al., J. Neurochemistry, 37, pp. 714-722 (1981).
Tomoda et al., Bull. Chem. Soc. Jpn., 72, pp. 1327-1334 (1999).
Loiseau et al., Eur. J. Med. Chem, 22, pp. 457-462 (1987).
Kempter et al., J. Prakt. Chem, 313, pp. 977-985 (1971).
Pentimalli et al., Boll. Sci. Fac. Chim. Ind. Bologna, 24, pp. 205-214 (1966).
Khim.-Farm. Zh., 4, pp. 20-26 (1970).
Barlin, Gordon B., Journal of Heterocyclic Chemistry, 35(5), pp. 1205-1217 (1998).
Almirante, Luigi et al., J. Med. Chem., 8(3), pp. 305-312 (1965).

Affiliated with

Also associated with

Rating

Substituted imidazo [1,2-a] pyridine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted imidazo [1,2-a] pyridine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted imidazo [1,2-a] pyridine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3437766