Pharmaceutical formulations containing a non-steroidal...

Details Pharmaceutical formulations containing a non-steroidal... Pharmaceutical formulations containing a non-steroidal...

2005-03-22

2005-03-22

Spear, James M. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S451000, C424S452000, C424S457000, C424S458000, C424S465000, C424S468000, C424S489000, C424S470000, C424S474000, C424S490000

Reexamination Certificate

active

06869615

ABSTRACT:
An oral solid dosage form includes a therapeutically effective amount of an NSAID and a proton pump inhibitor in an amount effective to inhibit or prevent gastrointestinal side effects normally associated with the NSAID. Also disclosed is a method of treating a human patient in need of antiinflammatory, analgesic and/or antipyretic therapy, comprising orally administering to the patient an oral pharmaceutical dosage form which includes a therapeutically effective amount of an NSAID and an amount of a proton pump inhibitor effective to substantially inhibit gastrointestinal side effects of the NSAID. The invention is further related to a method of prophylactically treating a human patient who is on a therapy known to have significant gastrointestinal side effects or is about to begin such a therapy, via concurrent administration of an NSAID and a proton pump inhibitor in a combination (single) oral dosage form.

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