Method for treating neuromuscular disorders and conditions...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S234100, C424S236100, C424S247100, C424S190100, C514S002600

Reexamination Certificate

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06872397

ABSTRACT:
A method of treating a patient suffering from a disease, disorder or condition includes the administration to the patient of a therapeutically effective amount of botulinum toxin of a selected serotype until the patient experiences loss of clinical response to the administered botulinum toxin and thereafter administering to the patient a therapeutically effective amount of another botulinum toxin of a different serotype.

REFERENCES:
patent: 5183462 (1993-02-01), Borodic
patent: 5298019 (1994-03-01), Borodic
patent: 5401243 (1995-03-01), Borodic
patent: 5696077 (1997-12-01), Johnson et al.
patent: WO 940081 (1994-01-01), None
patent: WO 9400481 (1994-01-01), None
patent: WO 9428922 (1994-12-01), None
patent: WO 9517904 (1995-07-01), None
Jankovic et al., 1991, New England J. of medicine, vol. 324, No. 17, pp. 1186-1194.*
Ludlow et al., 1992, New England J. of medicine, vol. 326, No. 5, pp. 349-350.*
Simpson, L., 1981., Pharmacol. Reviews, vol. 33, No. 3, pp. 155-188.*
The Merck Manual of diagnosis and therapy, 1987. Merck Sharp and Dohme Researck Laboratories, NJ. pp. 1449-1551, 1420-1421.*
Athena files US and Canadian Investigational New Drugs(INDs);ScripJun. 5, 1992; No. 1724, p29.
Athena Makers a Wise Move; Medical Advertising News, Nov. 1992, p4.
Athena Outlines Business Strategy; Marketletter; Oct. 5, 1992, p N/A.
Blasl, Juan et al.;Botulinum Neurotoxin A Selectively Cleaves the Synaptic Protein SNAP—25; Nature; vol. 365, Sep. 9, 1993, pp160-163.
Brin, Mitchell;Interventional Neurology; Treatment of Neurological Conditions With Local Infection of Botulinum Toxin; Arch. De Neurobiol.; 54, Supl. 3, 1991 pp 7-23.
Dasgupta, Bibhuti;The Structure of Botulinum Neurotoxin; Botulinum Neurotoxin and Tetanus Toxin; Edited by Simpson, Lance; pp 53-67, 1989.
Gjerstad, Leif et al.;Treatment of Focal Dystonias With Botulinum Toxin; Translation Attached;Tidsskr Nor Laegeforen nr; 21, 1991; 111; pp2637-2639.
Jankovic, Joseph et al.;Therapeutic User ofBotulinum Toxin; The New England Journal of Medicine; Apr. 25, 1991, pp 1186-1991.
Moyer, Elizabeth et al.;Botulinum Toxin Type B: Experimental and Clinical Experience; Therapy With botulinum Toxin; Edited by Jankovic, Joseph et al.; pp 71-85, 1994.
Moyer, E. D. et al.;Effects of Intramuscular Injection of Botulinum Toxin Type B in Nonhuman Primates: Botulinum and Tetanus Neurotoxins; Edited by Dasgupta, B. R., pp665-666, 1992.
National Institutes of Health Consensus Development Conference Statement:Clinical Use of Botulinum Toxin: http://text.nlm.nih.gov
ih/cdc/www/83txt.html ; 18 pp. 1-18, 1990.
Poewe, W. et al.:Experience with Botulinum Toxin in Cervical Dystonia; Therapy with Botulinum Toxin; Edited by Jankovic, Joseph, pp 267-278, 1994.
Schantz, Edward et al.;Properties and Use of Botulinum Toxin and Other Microbial Neurotoxins in Medicine; American Society for Microbiology; vol. 56, 1992, pp 80-95.
Scott, Alan B. et al.:Systemic Toxicity of Botulinum Toxin by Intramuscular Injection in the Monkey; Movement Disorders; vol. 3, No. 4, 1988, pp 333-335.
Simpson, Lance L.;Clinically Relevant Aspects of the Mechanism of Action of Botulinum Neurotoxin; Journal of Voice, vol. 6, No. 4, 1992, pp 358-364.
Simpson, Lance L.;The Origin Structure, and Pharmacological Activity of Botulinum Toxin; Pharmacological Reviews, vol. 33, No. 3, pp155-188, 1981.
Tsui, J.K. et al.:A Pilot Study on the Use of Botulinum Toxin in Spasmodic Torticollis; The Canadian Journal of Neurological Sciences, vol. 12, No. 4, Nov. 1985, pp 314-316.
Tsui, J.K. et al.:Botulinum Toxin Type B in the Treatment of Cervical Dystonia: A Pilot Study; Neurology, Nov. 1995, 45(11). pp 2109-2110.
Tsui, J.K. et al.:Local Treatment of Spasmodic Torticollis with Botulinum Toxin: Le Journal Canadien Des Sciences Neurologiques, vol. 14, No. 3 (Supplement), Aug. 1987. pp 533-535.
U.S. Food and Drug Administration;List of Orphan Designations and Approvals: http://www.fda.gov/orphan/designat/list.htm, 1984-1999, 6 pp out of 257.
Borodic, G.E., et al.,Botulinum B Toxin as an alternative to Botulinum A Toxin: A Histologic Study, Ophthalmic Plastic and Reconstructive Surgery, vol. 9, No. 3, pp 182-190, 1993.
Schantz, E.J., et al.,Properties and use of botulinum toxin and other microbial neurotoxins in medicine, Microbiological Reviews, Mar. 1992, pp. 80-99, vol. 56, No. 1.
Sellin, L.C., et al.,Different effects of types A and B botulinum toxin on transmitter release at the rat neuromuscular junction, Acta Physiolo Scand 1983, 119:127-133.

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