2,4-Di(hetero-)arylamino(-oxy)-5-substituted pyrimidines as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S275000, C544S324000, C544S325000, C544S317000, C544S326000, C544S327000, C544S328000, C544S329000

Reexamination Certificate

active

06838464

ABSTRACT:
Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.

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