Method of use of sonic hedgehog protein as a ligand for patched

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

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Reexamination Certificate

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06942988

ABSTRACT:
The invention relates to hedgehog proteins that are involved in signaling developmental processes. The proteins of the invention modulate differentiation of neural plate. Also provided are methods for identifying compounds that modulate early events in development and more particularly to methods to identify compounds that modulate differentiation of neural plate using hedgehog proteins as ligands for the patched receptor.

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