Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2005-04-19
2005-04-19
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C435S456000, C435S472000, C424S450000
Reexamination Certificate
active
06881576
ABSTRACT:
A polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.
REFERENCES:
patent: 6126964 (2000-10-01), Wolff et al.
patent: 6383811 (2002-05-01), Wolff et al.
Budker Vladimir G.
Hagstrom James E.
Trubetskoy Vladimir S.
Wolff Jon A.
Johnson Mark K.
Ketter James
Mirus Bio Corporation
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