Oligonucleotides and methods for the detection of chlamydia trac

Details Oligonucleotides and methods for the detection of chlamydia trac Oligonucleotides and methods for the detection of chlamydia trac

1993-09-03

1997-02-11

Arthur, Lisa B.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 912, 536 2432, 536 2433, 935 77, 935 78, C12Q 168, C12P 1934, C07H 2104

Patent

active

056019785

ABSTRACT:
The present invention relates to oligonucleotide probes useful in detecting, e.g. by hybridization or the ligase chain reaction, Chlamydia trachomatis DNA in the presence of other related DNA. The present invention is also directed to methods of detecting Chlamydia trachomatis organisms in a sample using the ligase chain reaction.

REFERENCES:
patent: 4683195 (1987-07-01), Mullis
patent: 5232829 (1993-08-01), Longiaru et al.
Stephens et al. (1987) J. Bact. 169(9): 3879-3885.
Baehr, Wolfgang, et al., Mapping Antigenic Domains Expressed by Chlamydia Trachomatis Major Outer Membrane Protein Genes, Proc. Natl. Acad. Sci. USA, vol. 85, pp. 4000-4004, Jun., 1988, Immunology.
Hatt, Christopher, et al., Analysis of the Entire Nucleotide Sequence of the Cryptic Plasmid of Chlamydia Trachomatis Serovar L1. Evidence for Involvement in DNA Replication, Nucleic Acids, vol. 16, No. 9, 1988, pp. 4053-4067.

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