Topical administration of basic antifungal compositions to...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S031000, C514S159000, C514S161000, C514S162000, C514S163000, C514S164000, C514S239500, C514S252010, C514S269000, C514S274000, C514S346000, C514S383000, C514S384000, C514S396000, C514S399000, C514S400000, C514S462000, C514S557000, C514S558000, C514S560000, C514S568000, C514S588000, C514S648000, C514S649000, C514S717000, C514S738000, C514S858000, C514S937000, C514S944000, C514S946000, C514S947000, C514S964000, C514S969000, C424S411000, C424S445000, C424S447000, C424S448000, C424S449000, C424S484000, C424S

Reexamination Certificate

active

06846837

ABSTRACT:
Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a pharmaceutically acceptable base in a formulation having a pH of 7.5 to about 13.0, preferably about 8.0 to 11.5, and most preferably about 8.5 to 10.5. These basic formulations permeate the nail and are effective in treating fungal infections of the nail and surrounding tissues.

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