Antibodies to cytokine receptor common gamma chain like

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S331000, C436S501000, C530S350000, C530S389100, C530S388220, C530S387300, C530S391700, C424S134100, C424S135100, C424S143100, C424S178100

Reexamination Certificate

active

06861227

ABSTRACT:
The present invention relates to a novel human gene encoding a polypeptide which is a member of the Cytokine Receptor family. More specifically, the present invention relates to a polynucleotide encoding a novel human polypeptide named Cytokine Receptor Common Gamma Chain Like, or “CRCGCL.” This invention also relates to CRCGCL polypeptides, as well as vectors, host cells, antibodies directed to CRCGCL polypeptides, and the recombinant methods for producing the same. Also provided are diagnostic methods for detecting disorders related to the immune system, and therapeutic methods for treating diagnosing, detecting, and/or preventing such disorders. The invention further relates to screening methods for identifying agonists and antagonists of CRCGCL activity.

REFERENCES:
patent: 5886157 (1999-03-01), Guengerich et al.
patent: 20020173623 (2002-11-01), Reche-Gallardo et al.
patent: 0578 932 (1994-01-01), None
patent: WO-9318047 (1993-09-01), None
patent: WO-9610074 (1996-04-01), None
patent: WO-9717360 (1997-05-01), None
patent: WO-9834631 (1998-08-01), None
patent: WO-9842738 (1998-10-01), None
patent: WO-9857989 (1998-12-01), None
patent: WO-0200723 (2002-01-01), None
patent: WO-0200724 (2002-01-01), None
patent: WO-02068646 (2002-09-01), None
patent: WO-03029423 (2003-04-01), None
GenEmbl Accession No. MMAA21949, Marra et al., “Cloning and chromosomal mapping of bovine inerleukin-2 receptor gamma gene” (1996).
Tonozuka et al., “Molecular coloning of a human novel type I cytokine receptor related to1/TSLPR,” Cytogenet Cell Genet 93:23-25 (2001).
Blagoev et al., “Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene,” Gene 284(1-2):161-168 (2002).
He et al., “The structure and function of gamma-c-dependent cytokines and receptors: Regulation of T lymphocyte development and homeostasis,” Immunology, 18:503-524 (1998).
Johnston et al., “Signaling by IL-2 and related cytokines: JAKs, STATs, and relationship to immunodeficiency,” J. Leukocyte Biol. 60:441-452 (1996).
Henthorn et al., “IL-2R-gamma Gene Microdeletion Demostrates that Canine X-Linked Severe Combined Immunodeficiency is a Homologue of the Human Disease,” Genomics 23:69-74 (1994).*
Yoo et al., “Cloning and chromosomal Mapping of Bovine Interleukin-2 Receptor Gamma Gene,” DNA Cell and Biology 15(6):453-459 (1996).*
Zhang et al., “Identification of a novel type l cytokine receptor CRL2 preferentially expressed by human dendritic cells and activated monocytes,” Biochem. and Biophys. Res. Commun. 281:878-883 (2001).*
Reche et al., “Human thymic stromal lymphopoietin preferentially stimulates myeloid cells,” J. Immunology 167:336-343 (2001).*
Lodish, H., eds. Molecular Cell Biology, p. 193 (1995).*
Ngo et al., “The Protein Folding Problem and Tertiary Structure: Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox,” eds. K. Merz, Jr. and S. LeGrand, pp. 491-495 (1990).*
Wells, James A., “Additivity of Mutational Effects in Proteins,” Biochemistry 29:8509-8517 (1990).*
Bowie et al., “Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,” Science, 247:1306-1310 (Mar. 1990).*
Townsend et al., “Peptide Mimics of the Cytokine Receptor Common Gamma Chain,” J. Allergy and Clin. Immun. 99(1):16 (1997).*
Watson et al., eds., The G-Protein Linked Receptor Facts Book, Academic Press, pp. 350-355 (1994).*
Callard et al., The Cytokine Facts Book, Academic Press, London (1994).*
GenEmbl Accession No. HSLAS41, Cook, P.R. “Sapiens DNA for loop attachment sequence (clone LAS41)” (Apr. 22, 1996).*
SwissProt 40 Accession No. P11371, Johnson et al., “Cytochrome P4502C4 (EC 1.14.14.1) (CYPIIC4)(Progesterone 21-hydroxylase)(P450 PBC4)(P1-88)” (Jul. 1, 1989).*
SwissProt 40 Accession No. P00180. Leighton et al., “Cytochrome P4502C1 (EC 1.14.14.1)(CYPIIC1)(Fragment)” (Jul. 1986).*
Alexander et al., “Altering the antigenicity of proteins,” PNAS 89:3352-3356 (1992).*
Ngo et al., The Protein Folding Problem and Tertiary Structure pp. 14-16.*
GenBank Accession No. X91553, Cook, P.R. (Apr. 22, 1996).*
GenBank Accession No. AK026800, Kawakami et al., “Homo sapiens cDNA: FLJ23147 fis, clone LNG09295,” (Sep. 12, 2003).*
GenBank Accession No. AC084255, Birren et al., “Homo sapiens clone RP11-257013, Low Pass Sequence Sampling,” (Oct. 18, 2000).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Antibodies to cytokine receptor common gamma chain like does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antibodies to cytokine receptor common gamma chain like, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antibodies to cytokine receptor common gamma chain like will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3404227

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.