Stable pharmaceutical compositions without a stabilizer

Details Stable pharmaceutical compositions without a stabilizer Stable pharmaceutical compositions without a stabilizer

2005-05-17

2005-05-17

Spear, James M. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S465000, C424S489000, C514S970000, C514S772300, C514S781000, C514S777000, C514S770000

Reexamination Certificate

active

06893660

ABSTRACT:
Stabilized controlled release pharmaceutical preparations are disclosed in which active ingredient degradation is prevented without the use of a stabilizer. The active ingredient is sealed away from excipients that can adversely affect stability by sealing the excipients rather than the active ingredient. The preparations are substantially unaffected by exposure to storage conditions of elevated temperature and/or elevated relative humidity.

REFERENCES:
patent: 2011587 (1935-08-01), Miller
patent: 2987445 (1961-06-01), Levesque
patent: 3143463 (1964-08-01), Holm et al.
patent: 3146169 (1964-08-01), Stephenson et al.
patent: 3538214 (1970-11-01), Polli et al.
patent: 3773920 (1973-11-01), Nakamoto et al.
patent: 3819706 (1974-06-01), Mehta
patent: 3885046 (1975-05-01), Mehta
patent: 3930032 (1975-12-01), Harris et al.
patent: 4016880 (1977-04-01), Theeuwes et al.
patent: 4060598 (1977-11-01), Groppenbacher et al.
patent: 4077407 (1978-03-01), Theeuwes et al.
patent: 4116241 (1978-09-01), Theeuwes et al.
patent: 4135514 (1979-01-01), Zaffaroni et al.
patent: 4173626 (1979-11-01), Dempski et al.
patent: 4256108 (1981-03-01), Theeuwes
patent: 4309405 (1982-01-01), Guley et al.
patent: 4327725 (1982-05-01), Cortese et al.
patent: 4393078 (1983-07-01), Peck
patent: 4435449 (1984-03-01), Stern
patent: 4438138 (1984-03-01), Stern
patent: 4439194 (1984-03-01), Harwood et al.
patent: 4507323 (1985-03-01), Stern
patent: 4519801 (1985-05-01), Edgren
patent: 4539198 (1985-09-01), Powell et al.
patent: 4557925 (1985-12-01), Lindahl et al.
patent: 4571395 (1986-02-01), Peck
patent: 4650669 (1987-03-01), Alexander et al.
patent: 4687660 (1987-08-01), Baker et al.
patent: 4769027 (1988-09-01), Baker et al.
patent: 4786505 (1988-11-01), Lovgren et al.
patent: 4798826 (1989-01-01), Peck
patent: 4853230 (1989-08-01), Lovgren et al.
patent: 4935429 (1990-06-01), Dackis et al.
patent: 5071646 (1991-12-01), Malkowska et al.
patent: 5098715 (1992-03-01), McCabe et al.
patent: 5358970 (1994-10-01), Ruff et al.
patent: 5427798 (1995-06-01), Ludwig et al.
patent: 5472708 (1995-12-01), Chen
patent: 5503846 (1996-04-01), Wehling et al.
patent: 5508040 (1996-04-01), Chen
patent: 5512593 (1996-04-01), Dante
patent: 5541231 (1996-07-01), Ruff et al.
patent: 5731000 (1998-03-01), Ruff et al.
patent: 5763493 (1998-06-01), Ruff et al.
patent: 5837379 (1998-11-01), Chen et al.
patent: 5968553 (1999-10-01), Maitra et al.
patent: 5990175 (1999-11-01), Pinsker
patent: 6033686 (2000-03-01), Seth
patent: 6096341 (2000-08-01), Seth
patent: 6110973 (2000-08-01), Young
patent: 6143327 (2000-11-01), Seth
patent: 6150420 (2000-11-01), Houdi et al.
patent: 6194002 (2001-02-01), Sherman
patent: 6197827 (2001-03-01), Cary
patent: 6210716 (2001-04-01), Chen et al.
patent: 6221917 (2001-04-01), Maitra et al.
patent: 6238697 (2001-05-01), Kumar et al.
patent: 6242496 (2001-06-01), Kulkarni et al.
patent: 6270805 (2001-08-01), Chen et al.
patent: 6277887 (2001-08-01), Young
patent: 6280763 (2001-08-01), Midha et al.
patent: 6306436 (2001-10-01), Chungi et al.
patent: 6312716 (2001-11-01), Midha et al.
patent: 6333332 (2001-12-01), Han et al.
patent: 6337328 (2002-01-01), Fang et al.
patent: 6342496 (2002-01-01), Jerussi et al.
patent: 6396113 (2002-05-01), Young
patent: WO 0030685 (2000-06-01), None
Physicians' Desk Reference 46th Edition 1992 pg. 821 “Wellbutrin”.
Cooper et al., Journal of Pharmaceutical Sciences, vol. 73, No. 8 Aug. 1984; “Determination of Bupropion and Its Major Basic Metabolites in Plasma by Liquid Chromatography with Dual-Wave Ultraviolet Detection” pp. 1104-1107.
Butz et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 217, No. 31981; “Radioimmunoassay and Pharmacokinetic Profile of Bupropion in the Dog” pp. 602-601.

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