Heteroaryl derivatives and their use as medicaments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S256000, C514S259500, C514S253060, C514S253070, C514S249000, C514S263210, C544S238000, C544S295000, C544S296000, C544S319000, C544S333000, C544S363000, C544S180000, C544S237000, C544S353000, C544S354000, C544S356000, C544S284000

Reexamination Certificate

active

06890926

ABSTRACT:
The invention relates to novel quinoline derivatives of the formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.

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Todd R. Elworthy, Anthony P.D.W. Ford, Gary W. Bantle, et al., N-Arylpiperazinyl-N′-propylamino Derivatives of Heteroaryl Amides as Functional Uroselective a1-Adrenoceptor Antagaonists, J. Med. Chem. 1997, 40 , 2674-2687.
Arthur G. Taveras, Jeff Deskus, Jianping Chao, Cynthia J. Caccaro, et al., Identification of Pharmacokinetically Stable 3,10-Dibromo-8-chlorobenzocycloheptapyridine Farnesyl Protein Transferase Inhibitors with Potent Enzyme and Cellular Activities, J. Med Chem. 1999, 42, 2651-2661.
El-Sebai A. Ibrahim, I. Chaaban and S. M. El-Khawass, Synthesis of Some Quinoline Derivatives of Potential Antiamebic Activity, Pharmazie 32, H. 3 (1977), 155-156.
Examination Report of the corresponding Chinese Patent Application.

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