Methods for the treatment of gastrointestinal disorders

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof

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514159, 514503, A61K 3324, A61K 3160, A61K 3129

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active

056018487

ABSTRACT:
Method for the treatment of human and lower animals having an infectious gastrointestinal disorder, comprising the step of administering from about 50 to about 5000 milligrams of bismuth to said subject, per day, for from 3 to 56 days. Preferred processes also include a step for performing a diagnostic step on the subject for detection of campylobacter-like organism infection of the subject.

REFERENCES:
patent: 3247051 (1966-04-01), Leebrick
patent: 3577533 (1971-05-01), Rider
patent: 4016268 (1977-04-01), Goldenberg et al.
patent: 4118480 (1978-10-01), Williams
patent: 4153685 (1979-05-01), Serfontein
Drugs 12:401-411 (Brogden et al) 1984.
The Lancet, Jun. 4, 1983, pp. 1273-1275.
Gastroenterology, 78(6):1495-1499 (Jun.) 1980.
Gastroenterology 82(5):864-70, May 1982.
The Medical Journal of Australia, vol. 142 Apr. 15, 1985 Marshall et al.
The New England Journal of Medicine, Dec. 10, 1981 pp. 1444-1452 Blaser.
The Lancet, Sep. 1, 1984, 525-526.
The Lancet, 16 Jun. 1984, pp. 1311-1315.
The Lancet, Aug. 4, 1984, p. 281; May 12, 1984 (McNulty).
Jour. DD. Oct. 1940 vol. VII No. 10 443-445.
The Lancet, Jun. 16, 1984, pp. 1348-1349 & 1336-1337.
Annales Pharmaceutiques Francaises, vol. 38, No. 5, pp. 447-454 (1980).
Chemical Abstracts Service (Columbus, Ohio) abstract, vol. 98, p. 15, No. 172475y (1983).
Chemical Abstracts Service (Columbus, Ohio) abstract, vol. 98, p. 384, No. 221850c (1983).
Steer, "Surface morphology of the gastroduodenal mucosa in duodenal ulceration", Gut, 25, pp. 1203-1210 (1984).
Marshall and Warren, "Spiral bacteria in the human stomach: a common finding in patients with gastritis and duodenal ulcer" in: Campylobacter II, Proceedings of the Second International Workship on Campylobacter Infections (London, 1983; Public Health Laboratory Service; Pearson, Skirrow et al., editors), pp. 11-12.
Abstract: "Histological Improvement of Active Chronic Gastritis in Patients Treated with De-Nol", presented at a meeting of the Gastroenterological Society of Australia, Mar. 11-14, 1984, Melbourne, Australia.
M. B. Skirrow, "Report on the Session" in Campylobacter II, Proceedings of the Second International Workshop on Campylobacter Infections (London, 1983; Public Health Laboratory Service; Pearson, Skirrow et al., editors), pp. 5-10.
"Bismosal, Mixture Cholera Infantum, Norwich" (Advertisement) (1918).
"Stomach Upset" (Advertisement) (1951).
B. J. Marshall, I. Hislop et al, "Histological Improvement of Active Chronic Gastritis in Patients Treated with De-Nol", 14 Australia & New Zealand J. of Medicine 907 (Dec., 1984).
B. J. Marshall, "Perspective-Campylobacter pyloridis and Gastritis" 153 J. of Infectious Diseases 650-657 (1986).
S. Zhang, et al., "Protective Effects of Furazolidone and Some Commonly Used Antiulcer Drugs on Several Gastric Ulcer Models in Rats", 19 Yaoxue Xuebao 5-11 (1984).
Physicians Desk Reference for Nonprescription Drugs 646 (1985).
L. Lu, et al., "Effect of Furaxon and It Analogs on Gastrointestinal Propulsion in Mice", 15 Beijing Yixueyuan Xuebao 185-187 (1983).
B. E. He, et al., "Cytoprotection of Furazolidone in Resistant-Soakage Gastric Ulcers in Rats", 4 Jinau Liyi Xuebao 55-59 (1984).
K. I. Shirokova, et al., "The Use of Metronidazole in Treatment of Patients with Ulcerative Disease", 59 Klin. Med.--(Mosk) 48-50 (1981).
Z. T. Zheng, et al., "Treatment of Gastrointestinal Ulcer by Furazolidone", 2 Chinese J. of Digestion 131-133 (1982).
Z. Zheng, et al., "Bouble-blind Short-term Trial of Furazolidone in Peptic Ulcer" 1 Lancet 1048-1049 (1985).
C. McNulty, et al., "Rapid Diagnosis of Campylobacter-Associated Gastritis" 1 Lancet 1443-1444 (1985).
A. McLean, et al., "Microbes, Peptic Ulcer and Relapse Rates with Different Drugs", 2 Lancet 525-526 (1984).
B. Marshall, et al., "Pyloric Campylobacter Infection and Gastroduodenal Disease" 142 Medical Journal of Australia 439-444 (1985).
R. Burnett, et al., "Campylobacter-like Organisms in the Stomach of Patients and Healthy Individuals" 1 Lancet 1349 (1984).
B. Marshall, et al., "Pyloric Campylobacter Serology" 2 Lancet 281 (1984).
B. Marshall, et al., "Unidentified Curved Bacilli in the Stomach of Patients with Gastritis and Peptic Ulceration" 1 Lancet 1311-1315 (1984).
M. Langenberg, et al., "Campylobacter-like Organisms in the Stomach of Patients and Healthy Individuals" 1 Lancet 1348 (1984).
Z. Zheng, et al., "A Double-blind Short-term Clinical Trial of the Effect of Furazolidone in Peptic Ulcer", 23 Chinese J. of Int. Medicine 195-197 (1984).
C. McNulty, et al., "Spiral Bacteria of the Gastric Antrum" 1 Lancet 1068 (1984).
J. Warren, "Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastitis" 1 Lancet 1273 (1983).
B. Marshall, "Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastitis" 1 Lancet 1273-1275 (1983).
J. Koo, et al., "Selective Coating of Gastric Ulcer by Tripotassium Dicitrato Bismuthate in the Rat", 82 Gastroenterology 864-870 (1982).
M. Gregory, "The Effect of Tri-potassium Di-citrato Bismuthate on the Duodenal Mucosa During Ulceration" 62 S.A. Medical Journal 52-55 (1982).
M. Steinhoff, et al., "Bismuth Subsalicylate Therapy of Viral Gastroenteritis", 78 Gastroenterology 1495-1499 (1980).
M. Blaser, et al., "Campylobacter Enteritis", 305 New England Journal of Medicine 1444-1452 (1981).
A. Freedberg, et al., "The Presence of Spirochetes in Human Gastric Mucosa", 7 American Journal of Digestive Diseases 443-445 (1940).
M. Goldenberg, et al., "Protective Effects of Pepto-Bismol Liquid on the Gastric Mucosa of Rats", 69 Gastroenterology 636-640 (1975).
Colson, "The treatment of chronic colitis and colopathies by a new association of bismuth, mucilage, oxyquinoline and meprobamate", Revue des corps de sante des Armees, 7(2), pp. 319-334 (1966).
Gisselbrecht et al., "Treatment of constipation and colitis by the association of bismuth subnitrate and Karaya gum", Lyon Med., 223(18), pp. 951-958 (1970).
Navarranne, "Treatment of spasmodic and psychosomatic colopathies by a cicatrisant, antiseptic and anxiolytic medication combination", Therapie, XXII, pp. 419-426 (1967).
Heraud et al., "Therapeutic trial of an association of an insoluble bismuth salt and a Karaya gum in gastro-intestinal pathology", Lille Medical, 3rd Series vol. XIV, No. 6, supplement, pp. 677-679 (1969).
Chemical Abstracts Service (Columbus, Ohio) abstract, vol. 94, p. 93, No. 168025b (1981).
Unlisted Drugs, vol. 22, No. 11, p. 163b (Nov. 1970), "Aldefur".
Biological Abstracts, vol. 82, No. 1626, abstract No. 1623 (1986).
Unlisted Drugs, vol. 34, No. 3, p. 38; (Mar. 1982), "Corygest".
Rote List 1976, Editio Cantor, Aulendorf, Wurtt, DE; "Uplex 59051B".

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