Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-07-19
2005-07-19
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S350000
Reexamination Certificate
active
06919340
ABSTRACT:
A novel composition comprises a compound of Formula 1the pharmaceutically acceptable salts, hydrates, solvates, crystal forms, diastereomers, prodrugs, or mixtures thereof. The composition is of particular utility in the treatment of kinase-implicated disorders.
REFERENCES:
patent: 5593997 (1997-01-01), Dow et al.
patent: 5658857 (1997-08-01), Andree et al.
patent: 5783576 (1998-07-01), Roos et al.
patent: 2004/0063715 (2004-04-01), Paruch et al.
patent: 2004/0067951 (2004-04-01), DeSimone et al.
patent: 2004/0072835 (2004-04-01), Paruch et al.
patent: 2004/0220189 (2004-11-01), Sun et al.
patent: 0 43 37 609 (1995-05-01), None
patent: 0 480 713 (1991-10-01), None
patent: WO 88/04298 (1988-06-01), None
patent: WO 95/12594 (1995-05-01), None
patent: WO 96/04298 (1996-02-01), None
patent: WO 96/34866 (1996-11-01), None
patent: WO 99/28322 (1999-06-01), None
patent: WO 01/27119 (2001-04-01), None
patent: WO 02/10170 (2002-02-01), None
patent: WO 02/30428 (2002-04-01), None
patent: WO 02/060492 (2002-08-01), None
patent: WO 02/076985 (2002-10-01), None
patent: WO 2003/089434 (2003-10-01), None
patent: WO 2004/022562 (2004-03-01), None
patent: WO 2004/026310 (2004-04-01), None
patent: WO 2004/026877 (2004-04-01), None
patent: WO 2004/072080 (2004-08-01), None
patent: WO 2004/072081 (2004-08-01), None
Banerjee et al, “Experimental Models of Colorectal Cancer” Diseases of the Colon and Rectum, vol. 41(4), pp. 490-505.
Ulrich et al, “Pancreatic Cell Lines: A Review” Pancreas, vol. 24(2), pp. 111-120 (2002).
International Search Report Dated Oct. 22, 2003.
Vitse, et al. “New Imidazo [1,2-a]pyrazine Derivatives with Bronchodilatory and Cyclic Nucleotide Phosphodiesterase Inhibitory Activities”. Bioorganic & Medicinal Chemistry 7 (1999) 1059-1065.
Hanks, Steven K. Protein Kinase Classification. 1994. pp. 1-4. http://pkr.sdsc.edu/html/pk_classification/pk_catalytic/pk_hanks_class.html.
Jeffrey, Trina K. et al. “Phosphodiesterase III and V Inhibitors on Pulmonary Artery from Pulmonary Hypertensive Rats: Differences Between Early and Established Pulmonary Hypertension.” Journal of Cardiovascular Pharmacology. 1998. vol. 32, pp. 213-219.
Lumma, William C. et al. “Piperazinylimidazo[1,2-a]pyrazines with Selective Affinity for in Vitro a-Adrenergic Receptor Subtypes.” J. Med. Chem. 1983. vol. 26, pp. 357-363.
“Protein Kinases in Disease.” http://bioinformatics.weizmann.ac.il/Kinases/pkr/pk_medicine.html.
Stenburg, Kaj A.E. et al. “KinMutBase, a database of human disease-causing protein kinase mutations.” Nucleic Acids Research. 2000. vol. 28, pp. 369-371.
International Search Report and Written Opinion dated Dec. 8, 2004, for Application No. PCT/US2004/021150, International filing date Jun. 30, 2004.
International Search Report and Written Opinion dated Dec. 30, 2004, for Application No. PCT/US2004/018227, International filing date Jun. 4, 2004.
Ding et al. (2002) “A Combinatorial Scaffold Approach toward Kinase-Directed Heterocycle Libraries,” JACS, 124(8): 1594-1596.
Written Opinion dated Dec. 5, 2003, for Application No. PCT/US03/12222, International filing date Apr. 21, 2003.
Second Written Opinion dated Apr. 13, 2004, for Application No. PCT/US03/12222, International filing date Apr. 21, 2003.
International Preliminary Examination Report dated Aug. 3, 2004, for Application No. PCT/US03/12222, International filing date Apr. 21, 2003.
International Search Report dated Feb. 9, 2004, for Application No. PCT/US03/28329, International filing date Sep. 9, 2003.
Written Opinion dated Jul. 6, 2004, for Application No. PCT/US03/28329, International filing date Sep. 9, 2003.
International Preliminary Examination Report dated Oct. 27, 2004, for Application No. PCT/US03/28329, International filing date Sep. 9, 2003.
International Search Report and Written Opinion dated Jul. 7, 2004, for Application No. PCT/US2004/003922, International filing date Feb. 10, 2004.
Currie Kevin S.
Darrow James W.
DeSimone Robert W.
Mitchell Scott A.
Pippin Douglas A.
Cellular Genomics, Inc.
Finnegan, Hednerson, Farabow, Garrett & Dunner
Tucker Zachary C.
Wilson James O.
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