Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Virus or bacteriophage
Patent
1995-09-11
1997-04-22
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Virus or bacteriophage
424 91, 424 932, 435 5, 435 6, A61K 4900, C12Q 168, C12Q 170
Patent
active
056226993
ABSTRACT:
The present invention provides methods for in vivo panning of a library to identify molecules that specifically home to a selected organ.
REFERENCES:
patent: 5081034 (1992-01-01), Bevilasqua et al.
patent: 5098833 (1992-03-01), Lasky et al.
patent: 5216131 (1993-06-01), Lasky et al.
patent: 5225538 (1993-07-01), Capon et al.
patent: 5288846 (1994-02-01), Quertermous et al.
patent: 5304640 (1994-04-01), Lasky et al.
patent: 5415874 (1995-05-01), Bender et al.
patent: 5428130 (1995-06-01), Capon et al.
patent: 5453362 (1995-09-01), Lamarco et al.
patent: 5506126 (1996-04-01), Seed et al.
Pasqualini et al., "Organ targeting in vivo using phage display peptide libraries", Nature 380: 364-366. Mar. 1996.
Hart et al., "Cell binding and internalization by filamentous phage displaying a cyclic Arg-Gly-Asp-containing peptide", J. Biol. Chem. 269: 12468-12474. Apr. 1994.
Goodson, Robert J. et al., "High-affinity Urokinase Receptor Antagonists Identified with Bacteriophage Peptide Display." Proc. Natl. Acad. Sci. USA. 91:7129-7133 (1994).
Burioni, Roberto et al., "Recombinant Human Fab to Glycoprotein D Neutralizes Infectivity and Prevents Cell-to-Cell Transmission of Herpes Simplex Viruses 1 and 2 In Vitro." Proc. Natl. Acad. Sci. USA 91:355-359 (1994).
Cattani, P et al., "Cloning and Characterization of Human Recombinant Antibody Fab Fragments Specific for Types 1 and 2 Herpes Simplex Virus." Chem. Abstr. Immunochemisty 123:141201m (1995).
Burton, Dennis R. et al., "A Large Array of Human Monoclonal Antibodies to Type 1 Human Immunodeficiency Virus From Combinatorial Libraries of Asymptomatic Seropostive Individuals." Proc. Natl. Acad. Sci. USA 88:10134-10137 (1991).
Cattani, P et al., "Cloning and Characterization of Human Recombinant Antibody Fab Fragments Specific for Types 1 and 2 Herpes simplex Virus." Microbiologica 18:135-142 (1995).
Pasqualini Renata
Ruoslahti Erkki
Chambers Jasemine C.
La Jolla Cancer Research Foundation
Priebe Scott D.
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