Biphosphonate conjugates and methods of making and using the...

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S001110, C424S001650, C424S009100, C534S010000, C534S014000, C514S089000, C514S107000, C514S108000, C546S022000, C546S024000

Reexamination Certificate

active

06896871

ABSTRACT:
The present invention is directed to particular bisphosphonate compounds, and in particular, to bisphosphonate conjugates that are useful in the treatment of soft tissues surrounding bone and bone-related diseases, such as bone cancer and osteoporosis.

REFERENCES:
patent: 4621077 (1986-11-01), Rosini
patent: 5130304 (1992-07-01), Binderup
patent: 5358941 (1994-10-01), Bechard
patent: 5488041 (1996-01-01), Barbier
patent: 6121253 (2000-09-01), Han et al.
patent: 6140518 (2000-10-01), Gallagher et al.
patent: 8800829 (1988-02-01), None
patent: 9110646 (1991-07-01), None
patent: WO 9835704 (1998-08-01), None
Hosain et al., “Targeted Delivery of Antineoplastic Agent to Bone: Biodistribution Studies of Technetium-99m-Labeled-Gem-Biphosphonate Conjugate of Methotrexate”, The Journal of Nuclear Medicine, vol. 37, No. 1, Jan. 1996.
Reinholz et al., “Distinct Mechanisms of Bisphosphonate Action Between Osteoblasts and Breast Cancer Cells: Identity of a Potent New Biophosphonate Analoque”, Breast Cancer Research and Treatment 71: 257-268, 2002.
Fleisch,Endocrine Reviews, 19(1), pp. 80-100 (1998).
Klein,Journal of Cellular Biochemistry, 68, pp. 186-194 (1998).
Rogers et al.,Molecular Pharmacology, 47, pp. 398-402 (1995).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Biphosphonate conjugates and methods of making and using the... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biphosphonate conjugates and methods of making and using the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biphosphonate conjugates and methods of making and using the... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3396937

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.