N-type calcium channel antagonists for the treatment of pain

Details N-type calcium channel antagonists for the treatment of pain N-type calcium channel antagonists for the treatment of pain

2005-01-11

2005-01-11

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S160000, C546S161000, C514S313000

Reexamination Certificate

active

06841680

ABSTRACT:
Compounds having selective action at neuronal N-type calcium channels useful for the treatment of pain in accord with the following structural diagram,wherein R1, R2and R3are a variety of groups as defined in the specification.

REFERENCES:
patent: 5506235 (1996-04-01), Moyer et al.
patent: WO 9303030 (1993-02-01), None
Marian Bala et al., “Synthesis and preliminary pharmacolo screening of 4-methylamino-2-phenylquinoline-3-carboxamides, p. 705, The Abstract No. 17614v, Pol. J. Pharmacol. Pharm. 1986, 38(1) 115-124,” Chemical Abstracts, vol. 106 (No. 21), p. 705, (May 25, 1987).

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