Size separation of analytes using monomeric surfactants

Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...

Reexamination Certificate

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C204S455000, C204S469000, C204S601000, C204S605000

Reexamination Certificate

active

06878254

ABSTRACT:
A sieving medium for use in the separation of analytes in a sample containing at least one such analyte comprises a monomeric non-ionic surfactant of the of the general formula, B-A, wherein A is a hydrophilic moiety and B is a hydrophobic moiety, present in a solvent at a concentration forming a self-assembled micelle configuration under selected conditions and having an aggregation number providing an equivalent weight capable of effecting the size separation of the sample solution so as to resolve a target analyte(s) in a solution containing the same, the size separation taking place in a chromatography or electrophoresis separation system.

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Liu et al, ACS Symposium Series (2000), 765, pp. 2-20.*
Rill et al, Chromatographia Supplement I, 49, 1999, pp. S65-S71.

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