Live, avirulent strain of V. anguillarum that protects fish...

Details Live, avirulent strain of V. anguillarum that protects fish... Live, avirulent strain of V. anguillarum that protects fish...

2005-07-05

2005-07-05

Graser, Jennifer E. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S200100, C424S190100, C435S243000, C435S252100, C435S252300, C435S173300

Reexamination Certificate

active

06913757

ABSTRACT:
The present invention comprises the identification, characterization and sequencing of a gene within theV. anguillarumgenome, the mugA gene, a live, attenuated strain ofV. anguillarumwhich comprises a mutated mugA gene, methods of making the strain, vaccines comprising the strain and methods of making such vaccines and administering the vaccines to animals. The invention further comprises vaccines comprised of proteins encoded by the mugA gene, to methods of making such vaccines and administering the vaccines to animals, to vectors comprised of the attenuated strain ofV.anguillarumand additional immunizing materials, methods of making the vectors and methods of administering the vectors to animals. Also disclosed are probes, passive vaccines and monoclonal antibodies for the detection and prevention of vibriosis.

REFERENCES:
patent: 5284653 (1994-02-01), Wolf-Watz et al.

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