Genetic markers for screening animals for improved disease...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S006120, C435S091100, C435S091200, C435S183000, C536S023100, C536S024300, C536S024310, C536S024330, C536S023500, C204S456000, C436S094000

Reexamination Certificate

active

06844159

ABSTRACT:
A method for determining improved innate immunity, disease resistance or performance in animals is disclosed. The method involves assays for a genetic differences in the NRAMP1 gene of the animal which is associated with superior disease resistance. Novel NRAMP1 sequence, assays, and compositions for identifying the presence of absence of these alleles are provided.

REFERENCES:
patent: 5200313 (1993-04-01), Carrico
patent: 6114118 (2000-09-01), Templeton et al.
patent: 6184031 (2001-02-01), Gros et al.
patent: 20020119455 (2002-08-01), Chan
patent: WO 9513371 (1995-05-01), None
patent: WO 952004 (1995-07-01), None
patent: WO 9812353 (1998-03-01), None
Zhang et al., Bioinformatics, vol. 19, No. 1, 2003, pp. 14-21.*
Graham et al. Identification of novel alleles at a polymorphic microsatellite repeat region in the human NRAMP1 gene promoter: analysis of allele frequencies in primary biliary cirrhosis.Journal of Medical Genetics. 2000:37 pp. 150-152.
Blackwell, Genetics and genomics in infectious disease susceptibility.Trends in Molecular Medicine. Nov. 2001:7(11) pp. 521-526.
Moisan et al. Clearance of Infection with Mycobacterium bovis BCG in Mice Is Enhanced by Treatment with S28463 (R-848), and Its Efficiency Depends on Expression of Wild-Type Nramp1 (Resistance Allele).Antimicrobial Agents and Chemotherapy, Nov. 2001:45(11) pp. 3059-3064.
Singal et al. NRAMP1 gene polymorphisms in patients with rheumatoid arthritis.Tissue Antigens, Jan. 2000:55 pp. 44-47.
Tuggle, et al., Rapid Communication: Cloning of a Pig Full-Length Natural Resistance Associated Macrophage Protein (NRAMP1) cDNA,J. Anlm. Sci. 1997, 75:277.
Sun, et al., Mapping of the natural resistance-associated macrophage protein 1 (NRAMP1) gene to pig chromosome 15, International Society for Animal Genetics,Animal Genetics, 1998, 29, 138-140.
Zhang, et al, Cloning of PorcineNRAMP1and its Induction by Lipopolysaccharide, Tumor Necrosis Factor Alpha, and Interleukin-1 Beta: Role of CD14 and Mitogen-Activated Protein Kinases,Infection and Immunity, Mar. 2000, p. 1086-1093.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Genetic markers for screening animals for improved disease... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Genetic markers for screening animals for improved disease..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Genetic markers for screening animals for improved disease... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3392873

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.