Immortalized avian cell lines

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or...

Reexamination Certificate

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C435S069100, C435S349000, C435S320100, C435S457000

Reexamination Certificate

active

06872561

ABSTRACT:
The invention features non-transformant immortal avian cells, in particular derived from avian tissues, i.e., other than blood or hematopoietic cells, particularly fibroblasts and epithelial cells, for instance of embryos. The avian cells are immortalized by the SV40 T+t gene in the dependence of the MTI promoter. In particular they integrate the pDAMT vector.

REFERENCES:
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patent: 6280970 (2001-08-01), Bouquet et al.
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patent: WO 9210563 (1992-06-01), None
patent: WO 9320200 (1993-10-01), None
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“Immortalization of human fibroblasts transformed by origin-defective simian virus 40”, Neufeld et al,Molecular and Cellular Biology, Aug. 1987, pp. 2794-2802.
“Overexpression of human cyclin A advances entry into S phase”, Rosenberg et al,Oncogene1995, vol. 10, pp. 1501-1509.
“Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis”, Gregory et al,Nature, Feb. 2, 1991, vol. 349, pp. 612-614.

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