Stepwise alkylation of 5-substituted...

Details Stepwise alkylation of 5-substituted... Stepwise alkylation of 5-substituted...

2005-03-08

2005-03-08

Trinh, Ba K. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C549S466000, C549S468000, C549S469000, C549S471000

Reexamination Certificate

active

06864379

ABSTRACT:
Methods for manufacture of citalopram through stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans are disclosed.

REFERENCES:
patent: 3467675 (1969-09-01), Petersen et al.
patent: 4136193 (1979-01-01), Bogeso et al.
patent: 4650884 (1987-03-01), Bogeso
patent: 4943590 (1990-07-01), Boegesoe et al.
patent: 5296507 (1994-03-01), Tanaka et al.
patent: 6020501 (2000-02-01), Massonne et al.
patent: 6028204 (2000-02-01), Massonne et al.
patent: 6229026 (2001-05-01), Petersen
patent: 6258842 (2001-07-01), Petersen et al.
patent: 6291689 (2001-09-01), Petersen et al.
patent: 6310222 (2001-10-01), Ikemoto et al.
patent: 6365747 (2002-04-01), Dall'Asta et al.
patent: 6392060 (2002-05-01), Petersen et al.
patent: 6403813 (2002-06-01), Petersen et al.
patent: 6407267 (2002-06-01), Rock et al.
patent: 6420574 (2002-07-01), Petersen et al.
patent: 6426422 (2002-07-01), Petersen et al.
patent: 6433196 (2002-08-01), Ikemoto et al.
patent: 6441201 (2002-08-01), Weber
patent: 6458973 (2002-10-01), Dall'Asta et al.
patent: 20020004604 (2002-01-01), Petersen et al.
patent: 20020026062 (2002-02-01), Petersen et al.
patent: 20020035277 (2002-03-01), Rock et al.
patent: 20020040153 (2002-04-01), Petersen
patent: 20020061925 (2002-05-01), Petersen et al.
patent: 20020077353 (2002-06-01), Petersen et al.
patent: 20020087012 (2002-07-01), Castellin et al.
patent: 20020120005 (2002-08-01), Villa et al.
patent: 20020128497 (2002-09-01), Bolzonella et al.
patent: 9819511 (1998-05-01), None
patent: 9819512 (1998-05-01), None
patent: 9819513 (1998-05-01), None
patent: 9930548 (1999-06-01), None
patent: 0011926 (2000-03-01), None
patent: 0012044 (2000-03-01), None
patent: 0013648 (2000-03-01), None
patent: 0023431 (2000-04-01), None
patent: 0039112 (2000-07-01), None
patent: 0044738 (2000-08-01), None
patent: 0145483 (2001-06-01), None
patent: 0147877 (2001-07-01), None
patent: 0147909 (2001-07-01), None
patent: 0149672 (2001-07-01), None
patent: 0151477 (2001-07-01), None
patent: 0151478 (2001-07-01), None
patent: 0162754 (2001-08-01), None
patent: 0166536 (2001-09-01), None
patent: 0168628 (2001-09-01), None
patent: 0168630 (2001-09-01), None
patent: 0168631 (2001-09-01), None
patent: 0168632 (2001-09-01), None
patent: 0185712 (2001-11-01), None
patent: 0204435 (2002-01-01), None
U.S. patent application Ser. No. 10/183,958, filed Jun. 25, 2002.
U.S. patent application Ser. No. 10/186,337, filed Jun. 27, 2002.
U.S. patent application Ser. No. 10/191,808, filed Jul. 8, 2002.
U.S. patent application Ser. No. 10/232,994, filed Aug. 29, 2002.
U.S. patent application Ser. No. 10/237,145, filed Sep. 5, 2002.
U.S. patent application Ser. No. 10/238,907, filed Sep. 6, 2002.
U.S. patent application Ser. No. 10/228,388, filed Aug. 23, 2002.
U.S. patent application Ser. No. 10/238,843, filed Sep. 9, 2002.
U.S. patent application Ser. No. 10/233,132, filed Aug. 30, 2002.
U.S. patent application Ser. No. 10/291,174, filed Nov. 8, 2002.
Levy, L.F., “4-Aminophthalide and Some Derivatives”,J. Chem. Soc. pp. 867-870 (1931).
Tirouflet, Jean, “Phtalide Substitués en 5”,Bull. Soc. Sci. de Bretagne26:35-43 (1951).
Forney, LeRoy S.., “Reaction of Terephthalic Acid with Formaldehyde in Sulfur Trioxide Media,”J. Org. Chem. 35:1695-1696 (1970).
Dordor, Isabelle M. et al., “Reaction of Oxazolines with Phosphorus Oxychloride,”Tetrahedron Letters24:1437-1440 (1983).
Barton, Sir Derek et al.,Comprehensive Organic Chemistry. The Synthesis and Reactions of Organic Compounds, vol. 2, pp. 1024-1025.
U.S. patent application Ser. No. 10/191,808, filed Jul. 8, 2002.
U.S. patent application Ser. No. 10/232,994, filed Aug. 29, 2002.
U.S. patent application Ser. No. 10/237,145, filed Sep. 5, 2002.
U.S. patent application Ser. No. 10/238,907, filed Sep. 6, 2002.
U.S. patent application Ser. No. 10/228,388, filed Aug. 23, 2002.
U.S. patent application Ser. No. 10/238,843, filed Sep. 9, 2002.
U.S. patent application Ser. No. 10/233,132, filed Aug. 30, 2002.
U.S. patent application Ser. No. 10/291,174, filed Nov. 8, 2002.
Levy, L.F., “4-Aminophthalide and Some Derivatives”,J. Chem. Soc. pp. 867-870 (1931).
Tirouflet, Jean, “Phtalide Substitués en 5”,Bull. Soc. Sci. de Bretagne26:35-43 (1951).
Forney, LeRoy S.., “Reaction of Terephthalic Acid with Formaldehyde in Sulfur Trioxide Media,”J. Org. Chem. 35:1695-1696 (1970).
Dordor, Isabelle M. et al., “Reaction of Oxazolines with Phosphorus Oxychloride,”Tetrahedron Letters24:1437-1440 (1983).
Barton, Sir Derek et al.,Comprehensive Organic Chemistry. The Synthesis and Reactions of Organic Compounds, vol. 2, pp. 1024-1025, 1978.
Bigler, Allan et al., Quantitative Structure-activity Relationships in a Series of Selective 5-HT uptake inhibitors,Eur. J. Med. Chem. 3:289-295 (1997).

Affiliated with

Also associated with

Rating

Stepwise alkylation of 5-substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stepwise alkylation of 5-substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stepwise alkylation of 5-substituted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3389328