Human mesencephalon cell lines and methods of use therefor

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

Reexamination Certificate

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C435S069100, C435S320100, C435S325000, C435S455000, C435S363000, C435S366000, C435S375000, C435S377000, C435S383000, C435S384000

Reexamination Certificate

active

06913925

ABSTRACT:
Conditionally-immortalized human mesencephalon cell lines are provided. Such cell lines, which may be clonal, may be used to generate neurons, including dopaminergic neurons. The cell lines and/or differentiated cells may be used for the development of therapeutic agents to prevent and treat a variety of neurological diseases such as Parkinson's disease. The cell lines and/or differentiated cells may also be used in assays and for the general study of mesencephalon cell development and differentiation.

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