Comestible for preventing calcium oxalate urolithiasis in...

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing

Reexamination Certificate

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C424S400000, C424S439000, C424S601000, C424S602000, C426S074000, C426S805000

Reexamination Certificate

active

06875450

ABSTRACT:
The present invention provides comestibles and related aspects for use in maintaining canine urinary tract health. In particular the comestibles and related aspects are useful in preventing the initial occurrence of canine calcium oxalate urolithiasis. The present invention also provides a comestible, which when fed to a small breed canine animal results in a urine specific gravity of 1.025 or below, for use in preventing the initial occurrence of calcium oxalate urolithiasis in the canine animal and related aspects. The comestible includes the following ingredients in the ranges indicated, for use in preventing the initial occurrence of calcium oxalate urolithiasis in a canine animal and related aspects:Nutrientg/400 kcalCalcium0.65-1.3Phosphorus0.5-1.2Magnesiumfrom 0.04Potassiumfrom 0.5Sodium0.6-1.2.

REFERENCES:
patent: 6133317 (2000-10-01), Hart
patent: 6156355 (2000-12-01), Shields, Jr. et al.
Stevenson, Abigail E., et al.; Effects of dietary potassium citrate supplementation on urine pH and urinary relative superstaturation of calcium oxalate and struvite in healthy dogs; AJVR, vol. 61, No. 4, Apr. 2000.
Bartges, Joseph W., et al.; Diet effect on activity product ratios of uric acid, sodium urate, and ammonium urate in urine formed by healthy Beagles; Am J Vet Res, vol. 56, No. 3, Mar. 1995.
Bartges, Joseph W., et al.; Influence of four diets on uric acid metabolism and endogenous acid production in healthy Beagles; AJVR, vol. 57, No. 3, Mar. 1996.
Lulich, Jody P., et al.; Epidemiology of Canine Calcium Oxalate Urolliths, Identifying Risk Factors; Veterinary Clinics of North America: Small Animal Practice, vol. 29, No. 1, Jan. 1999.

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