Surgery – Diagnostic testing – Cardiovascular
Reexamination Certificate
2005-05-03
2005-05-03
Hindenburg, Max F. (Department: 3736)
Surgery
Diagnostic testing
Cardiovascular
C600S481000, C600S508000, C607S017000
Reexamination Certificate
active
06887207
ABSTRACT:
A method and system incorporated into an IMD that detects changes in ventricular afterload using the morphology of a ventricular blood pressure wave. A peak positive pressure value Pb, peak positive and peak negative derivative pressures dP/dtPPand dP/dtNP, and a decreasing pressure Pcare determined. The sample times tb, at Pb, taat dP/dtPPand tcat dP/dtNPare determined. An index α of the relative timing of peak positive pressure Pbin the blood ejection phase is calculated from, α=(tb−ta)/(tc−ta), the severity of ventricular afterload is proportional to the value α in the range between 0 and 1. The slope of the early ejection pressure in the blood ejection phase is calculated from β=(Pc−Pb)/(tc−tb), wherein the severity of ventricular afterload is proportional to the magnitude of the index β.
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Hindenburg Max F.
Mallari Patricia
Medtronic Inc.
Soldner Michael C.
Wolde-Michael Girma
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