Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-03-29
2005-03-29
McKenzie, Thomas C. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S210180, C514S210190, C514S210200, C514S210210
Reexamination Certificate
active
06872717
ABSTRACT:
A method of treating or preventing obesity, this method comprising administering to a patient in need of such treatment an effective amount of a compound of formulain which R, R3and R4are as defined in the specification.
REFERENCES:
patent: 2507364 (1950-05-01), Benson
patent: 4260606 (1981-04-01), Cale
patent: 6022868 (2000-02-01), Olsen et al.
Barth F, Rinaldi-Carmona M., Curr Med Chem. Aug. 1999;6(8):745-55. Abstract only PMID: 10469889.*
Brotchie JM., Curr Opin Pharmacol. Feb. 2003;3(1):54-61, Abstract only PMID: 12550742.*
Ruiu S, Pinna GA, Marchese G, Mussinu JM, Saba P, Tambaro S, Casti P, Vargiu R, Pani L.J Pharmacol Exp Ther. Jul. 2003;306(1):363-70.*
Tzavara ET, Davis RJ, Perry KW, Li X, Salhoff C, Bymaster FP, Witkin JM, Nomikos GG, Br J Pharmacol. Feb. 2003;138(4):544-53.*
W. E. Bachmann;Journal of the American Chemical Society;“The Relative Stability of Penta-Arylethanes I. The Preparation of Penta-Arylethanes”; May, 1933; vol. 56; pp. 2135-2139.
A. L. Plasz et al.;Journal of the Chemical Society, Chemical Communications;“Photolytic Reduction of Phenyl Quinolin-3-yl Ketone to 3-Benzylquinoline”; 1972; pp. 527.
M. Hudlicky;ACS Monograph Series #186;“Oxidations in Organic Chemistry”; 1990; pp. 252-263.
G.A. Brine et al.;Journal of Heterocyclic Chemistry;“Carbon-13 Nuclear Magnetic Resonance Spectra of Fentanyl Analogs”; May-Jun. 1989; vol. 26; pp. 677-686.
D. Nagarathnam;Synthesis;“A Simple Synthesis of 2-Substituted Indoles”; Aug., 1992; pp. 743-745.
A. R. Katritzky et al.;Journal of Heterocyclic Chemistry;“Novel Syntheses of 1,3,3-Trinitroazetidine”; Mar.-Apr., 1994; vol. 31; pp. 271-275.
P. R. Dave;Journal of Organic Chemistry;“Acylative Dealkylation of N-tert-Butyl-3-substituted Azetidines: Facile Access to [1.1.0] Azabicyclobutane, 3-Hydroxyazetidinium Hydrochloride, and 3-Azetidinones”; 1996; vol. 61; pp. 5453-5455.
M. Grisar et al.;Journal of Medicinal Chemistry;“Benzhydryl and Fluorenyl Lactamides with Hypoglycemic, Diuretic, Blood Platelet Aggregation Inhibitory, and Antiinflammatory Activities”; 1973; vol. 16, No. 8; pp. 885-893.
N. G. Kundu et al.;Journal of the Chemical Society, Perkin Transactions 1;“Palladium-catalysed heteroannulation with acetylenic compounds: synthesis of benzofurnas”; 1997; pp. 2815-2820.
M. Moreno-Mañas et al.;European Journal of Medicinal Chemistry;“New imidazole and anti-fungal agents derived from benzo[β]thiophene. Part II”; 1988; vol. 23; pp. 477-482.
Skinner et al.;Journal of Medicinal Chemistry;“Antiviral Agents. 1. Benzothiazol and Benzoxazole Analogs of 2-(α-Hydroxybenzyl)benzimidazole”; 1971; vol. 14, No. 6; pp. 546-549.
N. K. Harn;Tetrahedron Letters;“Acylation of Oxazoles by the Copper-Mediated Reaction of Oxazol-2-ylzinc Chloride Derivatives”; 1955; vol. 36, No. 52; pp. 9453-9456.
A. Medici et al.;Tetrahedron Letters;“Reactions of 2-Trimethylsilylthiazole with Acyl Chlorides and Aldehydes Synthesis of New Thiazol-2-YL Derivatives”; 1983; vol. 24, No. 28; pp. 2901-2904.
R. D. Riecke et al.;Journal of Organic Chemistry;“Direct Preparation of 3-Thienyl Organometallic Reagents: 3-Thienylzinc and 3-Thienylmagnesium Iodides and 3-Thienylmanganese Bromides and Their Coupling Reactions”; 1997; vol. 62, No. 20; pp. 6921-6927.
J. Knabe et al.;Archives of Pharmacology;“Synthese von 1-Acylisochinolinen über Reissert-Verbindungen”; 1973; vol. 306(9), pp. 648-658.
R. Consonni et al.;Journal of the Chemical Society—Perkin Transactions 1;“Diels-Alder reactions of N-sulfonyl substituted aza-ortho-xylylenes generated from the corresponding 1,4-dihydro-2H-3,1-benzoxazin-2-one derivatives”; 1996; pp. 1809-1814.
L. Brandsma et al.;Synthetic Communications;“A Large-Scale Procedure for the Preparation of 3-Bromothiophene From 2-Bromothiophene and Sodamide in Liguid Ammonia”; 1990, vol. 20(11); pp. 1697-1700.
M. Lemaire et al.;Synthetic Communications;“A Convenient Synthesis of 3-fluorothiophene”; 1994; vol. 24(11); pp. 95-101.
H. Goda et al.;Synthesis;“Facile Synthesis of 5-Substituted 2-Acetylthiophenes”; 1992; vol. 9; pp. 849-851.
P. Baeuerle et al.;Journal of the Chemical Society—Perken Transactions 2;“Synthesis and Structural Characterization of Alkyl Oligothiophenes—The First Isomerically Pure Dialkylsexithiophene”; 1993; pp. 489-494.
P. Bouyssou et al.;Journal of Heterocyclic Chemistry;“Synthesis of 7- and 5,7-Substituted-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinolines: Convenient Precursors of Quinolone Antibacterial Agents”; 1992; vol. 29(4); pp. 895-898.
N. Suzuki et al.;Journal of the Chemical Society, Chemical Communications;“Synthetic Reactions in Polyethylene Glycol. Diazotization and Sandmeyer Reactions of Anilines in Polyethylene Glycol-Methylene Dichloride”; 1984; pp. 1523-1524.
S. Marburg et al.;Journal of Heterocyclic Chemistry;“A Short Efficient Synthesis of 4-Amino-2,3-dihydrobenzofuran”; 1980; vol. 17; pp. 1333-1335.
V. Percec et al.;Journal of Organic Chemistry;“Aryl Mesylates in Metal Catalyzed Homo- and Cross-Coupling Reactions. 4. Scope and Limitations of Aryl Mesylates in Nickel Catalyzed Cross-Coupling Reactions”; 1995; vol. 60(21); pp. 6895-6903.
J. F. Hansen et al.;Journal of Heterocyclic Chemistry;“Synthesis Studies Leading to DE-Ring Analogs of Camptothecin (1)”; 1973; vol. 10; pp. 711-714.
L. E. Hollister;Pharmacological Reviews;“Health Aspects of Cannabis*”; 1986; vol. 38; pp. 1-20.
S. Renu;Progress in Drug Research;“Chemistry and Pharmacology of Cannabis”; 1991; vol. 36; pp. 71-115.
S. Consroe;Marijuana/Cannabinoids: Neurobiology and Neurophysiology(Eds. Murphy, L.; Barthe. A.); “Potential Role of Cannabinoids for Therapy of Neurological Disorders”; 1992; pp. 459-524.
J. E. Kuster; J. I. Stevenson et al.;Journal of Pharmacology and Experimental Therapeutics;“Aminoalkylindole Binding in Rat Cerebellum: Selective Displacement by Natural and Synthetic Cannabinoids”; 1993; vol. 264; pp. 1352-1363.
T. Hayashi et al;Journal of the American Chemicl Society;“Dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium-(II): An Effective Catalyst for Cross-Coupling of Secondary and Primary Alkyl Grignard and Alkylzinc Reagents with Organic Halides”; 1984; vol. 106; pp. 158-163.
J. Wityak et al.;Bioorganic and Medicinal Chemistry Letters;“Synthesis and Antiplatelet Activity of DMP 757 Analogs”; 1994; vol. 5(18); pp. 2097-2100.
M. Desai; L Stramiello;Tetrahedron Letters;“Polymer Bound EDC (P-EDC): A Convenient Reagent for Formation of an Amide Bond”; 1993; vol. 34(48); pp. 7685-7688.
G. Pandey; T. D. Bagul et al.;Journal of Organic Chemistry:“[3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides. 7. Stereoselective Synthesis of Epibatidine and Analogues”; 1998; vol. 63; pp. 760-768.
A. G. Anderson; R. Lok;Journal of Organic Chemistry;“The Synthesis of Azetidine-3-carboxylic Acid”; 1972; vol. 37; pp. 3953-3955.
Achard Daniel
Bouchard Herve
Bouquerel Jean
Filoche Bruno
Grisoni Serge
Aventis Pharma S.A.
McKenzie Thomas C.
Newman Irving
LandOfFree
Pharmacological uses of azetidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pharmacological uses of azetidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmacological uses of azetidine derivatives will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3385371