Isolated human drug-metabolizing proteins, nucleic acid...

Details Isolated human drug-metabolizing proteins, nucleic acid... Isolated human drug-metabolizing proteins, nucleic acid...

2005-09-27

2005-09-27

Nguyen, Dave T. (Department: 1636)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

C424S094100

Reexamination Certificate

active

06949371

ABSTRACT:
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.

REFERENCES:
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Matsubara et al. “Complementary DNA Cloning and Inducible Expression During Pregnancy of the Messenger RNA for Rabbit Pulmonary Prostaglandin Omega Hydroxylase Cytochrome P-450-P-2.” Journal of Biological Chemistry, vol. 262, No. 27, 1987, pp. 13366-13371, XP002241281.
NCI-CGAP. “oh04f03.sl NCI_CGAP_KID3 Homo Sapiens cDNA Clone Image:1456829 3' Similar to SW:CP48_RAT P24464 Cytochrome P450 IVA8; mRNA Sequence.” Database EMBL 'Online! Mar. 15, 1998. Database accession No. AA863360. XP002241282.
NCI-CGAP . “n181a02.s1 NCI_CGAP-Br2 Homo Sapiens cDNA Clone Image:1057034 3' mRNA Sequence.” Database EMBL 'Online! Sep. 11, 1997. Database accession No. AA557324. XP002241283.
Database GENSEQ 'Online! Dec. 17, 2001. Database accession No. AAS40801. XP002241284.
International Search report dated May 23, 2003.

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