Sulfonamide compounds and uses thereof as medicines

Details Sulfonamide compounds and uses thereof as medicines Sulfonamide compounds and uses thereof as medicines

2005-05-10

2005-05-10

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S118000

Reexamination Certificate

active

06890934

ABSTRACT:
The present invention relates to a sulfonamide compound of the formula (I):wherein each symbol is as defined in the specification, a salt thereof, and a pharmaceutical composition containing same. This compound can be an effective agent for the prophylaxis and treatment of the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy suppressing action.

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H.T. Beauchamp, et al., The Journal of Pharmacology and Experimental Therapeutics, vol. 272, No. 2, pps. 612-618, “In vivo Receptor Occupancy of the Angiotensin II Receptor by Nonpeptide Antagonists: Relationship to in vitro Affinities and in vivo Pharmacologic Potency,” 1995.

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