Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-03-15
2005-03-15
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S329000, C514S331000, C546S193000, C546S223000, C546S232000
Reexamination Certificate
active
06867220
ABSTRACT:
The invention relates to compounds of formula (I)whereR1represents a hydrogen or halogen atom or an —S(O)z—(C1-C4)alkyl, —S(O)z—(C1-C4)R3, —SO2—NH—(C1-C4)alkyl, —NHCO(C1-C4) alkyl, —CO(C1-C4)alkyl or —NHSO2—(C1-C4)alkyl group;m and n independently represent 0, 1 or 2;A represents a group of formula (a) or (b):whereX is N or CH;R2represents an —SO2—R3, —CO—R3or —CO—(C1-C4)—alkyl group;R3represents a phenyl group, optionally substituted by a (C1-C4)alkyl or (C1-C4)alkoxy group, one or two halogen atoms or a heterocycle;R4represents a hydrogen or halogen atom or a (C1-C6)alkyl, (C1-C4)alkoxy, —COOH, —COO(C1-C4)alkyl, —CN, —CONR5R6, —NO2, —NHSO2(C1-C4)alkyl or —SO2NR5R6group;z is 1 or 2;R5and R6independently represent a hydrogen atom or a (C1-C4)alkyl, phenyl or phenyl (C1-C4)alkyl group;and their salts or solvates, to a process for their preparation, to synthetic intermediates and to the pharmaceutical compositions comprising them.
REFERENCES:
patent: 5627196 (1997-05-01), Audia et al.
patent: 5948792 (1999-09-01), Tsuchiya
patent: 6444685 (2002-09-01), Sun et al.
patent: 6525202 (2003-02-01), Hu et al.
patent: 20030144326 (2003-07-01), Hu et al.
patent: 35 24 955 (1986-01-01), None
patent: 095 454 (1983-11-01), None
patent: WO 99 52872 (1999-10-01), None
patent: WO 99 65895 (1999-12-01), None
Greene “Protective groups in organic synthesis” Wiley & Sons, p. 218-19, 232, 236 (1982).*
Spatola et al. “Amide bond surrogates . . . ” Tetrahedron v.44 p. 821-826(1988).*
Fisher et al. “Substituted sulfonamides . . . ” CA 125:221588 (1996).*
Brazzell et al. “Treatment of glaucoma . . . ” CA 126:1213 (1996).*
Wermuth C. G. “The practice of medicinal chemistry” Acad. pres. p. 207-217 (1996).*
Hu et al. “Preparation of cyclic amine . . . ” CA 136:134676 (2002).*
Shey et al. “Liquid phase combinatoryal . . . ” CA 130:296679 (1999).*
Mitsuya et al. “A potent long acting . . . ” CA 134:147471 (2000).*
Sum et al. “prepartion of (2-hydroethylamino)cyclicamino . . . ” CA 136:134678 (2002).*
M. Hori et al.; Journal of Organic Chemistry, vol. 63, no. 3; pp 889-894 (1998).
Chemical Abstract No. 131:299455 (1999).
Derwent Patent Abstract No. 198605 (2002).
Derwent Patent Abstract No. 198349 (2002).
Derwent Patent Abstract No. 200011 (2002).
Alexander Michael D.
Chang Celia
Sanofi-Synthelabo
LandOfFree
Phenoxypropanolamines, method for producing them and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Phenoxypropanolamines, method for producing them and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenoxypropanolamines, method for producing them and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3376829