Method and apparatus for signalling the introduction of chemical

Details Method and apparatus for signalling the introduction of chemical Method and apparatus for signalling the introduction of chemical

1976-06-02

1978-07-18

Reese, Robert M.

Chemistry: physical processes

Physical processes

Crystallization

23253R, 356 39, 250461B, G01N 2138, G01N 3316

Patent

active

041012763

ABSTRACT:
A system for chemically analyzing antigens or antibodies by initiating an antigen-antibody reaction in a reaction zone and measuring the light scattered by a precipitate produced by the reaction to determine the antigen or antibody concentration. In order to signal the start of the reaction, a fluorescent tagging substance is included with at least the last antigen or antibody reaction component introduced into the reaction zone. The fluorescent tagging substance does not enter into the antigen-antibody reaction and is selected to emit light in a bandwidth spectrally separated from the light scattered by the precipitate. The reaction zone is monitored for the presence of the tagging substance, and when the substance is detected a trigger signal is generated to signal the start of the reaction. By including a tagging substance with each component of the reaction and by monitoring the reaction zone for the presence of each tagging substance, a trigger signal is generated only if each reaction component is present.

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patent: 3850525 (1974-11-01), Kaye
patent: 3905767 (1975-09-01), Morris et al.
patent: 3971951 (1976-07-01), Rikukawa et al.
patent: 3974269 (1976-08-01), Maley

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