Spiro-lactams and analogs thereof useful as aldose reductase inh

Details Spiro-lactams and analogs thereof useful as aldose reductase inh Spiro-lactams and analogs thereof useful as aldose reductase inh

1991-07-12

1992-07-14

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546142, 549285, 514866, C07D47110, C07D21724, C07D21726, A61K 3147

Patent

active

051304252

ABSTRACT:
This invention relates to spiro-lactams and their pharmaceutically acceptable salts thereof, to processes for their preparation, to methods for using the compounds, and to pharmaceutical preparations thereof. The compounds have pharmaceutical properties which render them beneficial for the prevention or treatment of diabetes mellitus associated complications.

REFERENCES:
patent: 3870721 (1975-03-01), Archibald et al.
patent: 4927831 (1990-05-01), Malamas
Martel, Can J. Chem 55, 48(1977).

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