Method of reducing dental caries

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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424 48, 424 49, 424 54, 426 3, 426648, 426660, A61K 31425, A61K 968, A61K 716, A61K 722

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active

042910455

ABSTRACT:
A method for treating teeth to reduce caries is provided wherein the teeth are contacted with a saccharin material, optionally in the presence of a sugar, for example, as contained in a chewing gum composition, the saccharin material being present in an amount sufficient to inhibit growth of Streptococcus mutans in the oral cavity or on the teeth.

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Linke, H. et al., Z. Naturforsch, C. Biosci. 1976, 31C (5-6): 245-251 Physiological Effects of Sucrose Substitutes and Artificial Sweeteners on Growth Pattern and Acid Production of Glucose-Grown Streptococcus mutans Strains in Vitro.
Linke, H., Z. Naturforsch, C. Biosci. 1977, 32C (9-10): 839-843 Growth Inhibition of Glucose-Grown Cariogenic and Other Streptococci by Saccharin in Vitro.

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