Oxoimidazoquinoxalines

Details Oxoimidazoquinoxalines Oxoimidazoquinoxalines

1980-02-04

1981-09-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

42424853, 42424855, 544 64, 544115, 544225, 544346, C07D48704, A61K 31495

Patent

active

042910331

ABSTRACT:
Novel oxoimidazoquinoxalines of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, chlorine and bromine, X is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkyl of 3 to 5 carbon atoms and cycloalkyl-alkyl of 4 to 6 carbon atoms, R.sub.3 is selected from the group consisting of hydrogen alkyl of 1 to 5 carbon atoms, alkali metal, alkaline earth metal, aluminum, --NH.sub.4, organic amine and ##STR2## R.sub.4 and R.sub.5 are individually alkyl of 1 to 5 carbon atoms or taken together with the nitrogen atom form a saturated heterocycle of 4 to 6 carbon atoms optionally containing an oxygen atom or second nitrogen atom and n is a number from 1 to 5 and their non-toxic, pharmaceutically acceptable acid addition salts having antiallergic activity and their preparation.

REFERENCES:
patent: 3887566 (1975-06-01), Rodway et al.
patent: 3994893 (1976-11-01), Treuner
patent: 4075343 (1978-02-01), Kadin
patent: 4145419 (1979-03-01), Rowlands et al.
patent: 4151280 (1979-04-01), Rowlands et al.
patent: 4207318 (1980-06-01), Rowlands et al.

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