Pyrimidine-4,6-dicarboxylic acid diamides, processes for the use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514211, 514212, 514218, 5142278, 5142322, 5142358, 5142362, 5142365, 514245, 514252, 514269, 514272, 514270, 514271, 514274, 514275, 540544, 540575, 540601, 544122, 544123, 544120, 544121, 544114, 544113, 544 82, 544 83, A61K 3153, A61K 31505, A61K 3150, A61K 31495

Patent

active

051303175

ABSTRACT:
Pyrimidine-4,6-dicarboxylic acid diamides, processes for the use thereof, and pharmaceuticals based on these compounds
The invention relates to pyrimidine-4,6-dicarboxylic acid diamides of the formula I ##STR1## in which R.sup.1 and R.sup.2 have the meanings given. The compounds according to the invention inhibit proline hydroxylase and lysine hydroxylase and can be employed as fibrosuppressants and immunosuppressants.

REFERENCES:
patent: 5010200 (1991-04-01), McDonald et al.

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