Feedback-controlled LED switching

Electric lamp and discharge devices: systems – With radiant energy sensitive control means

Reexamination Certificate

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Details

C315S291000, C315S307000, C356S041000, C372S038020, C600S310000, C600S323000

Reexamination Certificate

active

06825619

ABSTRACT:

BACKGROUND
1. Field of the Invention
The present invention relates generally to feedback-controlled switching and, more particularly, to pulse oximetry having feedback-controlled LED switching where noise in a sense current and in LED drive current are reduced by switching a reference voltage in the feedback loop of an op-amp circuit.
2. Related Work
A pulse oximeter is a type of blood gas monitor which non-invasively measures an amount of saturation of oxygen in the blood. The saturation of oxygenated blood may be determined from the differentiated absorption for two plethysmographic waveforms measured at separate wavelengths. The two waveforms are typically produced by driving a visible red light-emitting diode (LED) and an infra-red LED to produce two lights that pass through a patient's tissue, and then detecting the light on the same or an opposite side of the tissue using one or more photodetectors. Although most conventional oximeters use the red and infra-red LEDs, other devices such as surface emitting laser devices having different wavelengths may also be used, and the number of LEDs can vary according to the specific measurement application. For example, it is known to set a number of laser diodes to be equal to or greater than the number of blood analytes that are to be measured by an instrument
The two LEDs emit light at different wavelengths. The photodetector output signal indicates the attenuation of the two different wavelength lights after the lights pass through the patient's body. In order to obtain a degree of consistency and ease of use, the photodetector is generally placed in a clip or similar device attached to the patient's finger or earlobe. Attenuation of the lights is substantially constant except for the flow of blood. Thus, the constant attenuation due to the light passing through the patient's skin and other tissue can be determined and filtered from the photodetector signal, thereby obtaining a signal representing the desired blood oxygen characteristics. Signals containing a component related to a patient's pulse are known as plethysmographic waves and are used in blood gas saturation measurements. So, for example, the red/infrared ratio for waveforms at different wavelengths may be analyzed to obtain oxygenization values.
It is known to activate the red and infra-red LEDs during different time periods, where the two LEDs are cycled on and off alternately, in order to enable the photodetector to receive one signal at a time. As a result of generating LED pulse trains in a time-division manner, a composite time-division signal is then received by the photodetector. Alternatively, switching of LEDs may be related to other parameters such as maintaining a particular duty cycle without regard to time-division multiplexing (TDM). Various methods, not limited to TDM or to periodic switching, for modulating the LEDs can also be employed.
In order to increase the accuracy and resolution of the oximeter, it is desirable to reduce noise in the circuitry used to produce one or more drive currents for causing the LEDs to illuminate. Conventional LED drive circuits have been designed to minimize photic noise generated by the LEDs, in order to maximize a signal-to-noise ratio for the arterial attenuation signal(s) used in processing oximetry data. However, as is further discussed below, conventional LED driving circuits do not consider that a switching of a reference voltage may be a source of noise.
A typical apparatus employing a time-division diode driving scheme includes LED current drivers having a serial configuration where the outputs of two voltage-to-current converters are switched so that only one of two LEDs, connected in a back-to-back configuration, is on at any given time. The LED drive circuitry activates the red LED for a quarter cycle and activates the infra-red LED for a quarter cycle, with a quarter cycle “dark” period separating each successive activation period. Since the two LEDs are on only periodically, less noise is generated from the LEDs and corresponding LED drive circuitry. This conventional LED drive circuitry uses ganged-type switch banks to alternately switch on/off both the input and the output of each voltage-to-current converter, thereby reducing noise from both the switching and voltage-to-current conversion circuitry. Both the reference voltage input and the resultant drive current output of a conventional dual LED drive circuit are simultaneously switched off because merely setting the reference set point to zero does not account for offset voltages in the op-amp that keep the op-amp in a “turned-on” state and that keeps the LED drive current turned on. The LEDs are thus driven to provide light transmission with digital modulation at a fixed low frequency f, where each period 1/f contains the aforementioned four quarter-cycle periods.
As shown in
FIG. 3
, a conventional LED drive circuit includes a reference voltage source
324
that generates an analog output, which is fed to a digital-to-analog (D/A) converter
325
. The output of the D/A
325
is then output to a switch bank
326
. When the switch bank
326
is in an ON condition, the D/A output signal is switchably connected to one of two voltage-to-current (V/I) converters
328
,
329
. When the switch bank
326
is in an OFF condition, the D/A output signal is switchably connected to the other of the two V/I converters
328
,
329
. The output of the currently activated V/I
328
,
329
is connected to a pair of back-to-back LEDs
301
,
302
via a second switch bank
327
, which disconnects the output of the currently deactivated V/I converter
328
,
329
from the LEDs
301
,
302
.
A conventional LED drive circuit, such as that described above, switches the reference voltage to each V/I converter. This conventional switching of the reference voltage creates a noise that is then amplified by the respective V/I converter. Although the conventional switching described above disables both the input and output of serially-oriented LED drivers, resulting in less overall average LED drive circuitry noise, it does not consider the noise created by the switching itself.
Oximetry noise is known to those of ordinary skill in the oximetry art to include any signal portions relating to ambient light, motion artifacts, absorption variance other than the plethysmographic effects of interest, electromagnetic radiation, electrical interference, magnetic fields, electronic interference such as harmonics or RF, and others.
Conventional voltage reference sources are chosen for use as a low noise DC voltage reference for a digital to analog conversion circuit
325
. In that regard, the conventional voltage reference of
FIG. 3
has a lowpass output filter (not shown) with a low corner frequency of 1 Hz. The digital to analog converter
325
also has a lowpass filter at its output with a similar low corner frequency of 1 Hz. The digital to analog converter
325
provides signals for each of the emitters
301
,
302
.
In the conventional
FIG. 3
circuit, voltage to current converters
328
,
329
can each have a feedback loop (not shown) that is configured to have a low pass filter to reduce noise. The low pass filtering function of the voltage to current converter
328
,
329
has a corner frequency of just above 625 Hz, which is the switching speed for the emitters
301
,
302
.
Other filters (not shown) are typically used to reduce the effects of ambient electromagnetic noise in electronic monitoring instruments, especially when the noise source frequency (or a harmonic of the noise source frequency) is approximately the same as the fundamental frequency or harmonics at which the instrument is operating. In addition, a static filtering using a bandpass filter has been conventionally used to remove a portion of the photodetector's output noise signal that is outside an identified bandwidth of interest, leaving random and/or erratic noise that is within the filter's passband. A processor has conventionally been used to separate-out primary signa

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