Use of nitrofurantoin for the treatment and prophylaxis of gastr

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514927, A61K 31415

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active

049593846

ABSTRACT:
The invention involves methods for the treatment and prophylaxis of human or animal subjects having infectious gastrointestinal disorders of the upper gastrointestinal tract caused or mediated by Campylobacter-like organisms comprising the step of administering to the subjects safe and effective amounts of nitrofurantoin.

REFERENCES:
Physicians' Desk Reference (PDR), 38 Edition, pp. 3395-1936, (1984).
Marshall, B. J., "Campylobacter pyloridis and Gastritis", The Journal of Infectious Diseases, vol. 153, No. 4, (Apr. 1986), pp. 650-657.
Goodwin, C. S., J. A. Armstrong and B. J. Marshall, "Campylobacter pyloridis, Gastritis, and Peptic Ulceration", Journal of Clinical Pathology, vol. 39, No. 4, (Apr. 1986), pp. 353-365.
Smith, J. S., G. E. Buck and D. Niesel, "Genetic Relationship of Campylobacter pyloridis to Other Species of Campylobacter", Abstracts of the Annual Meeting, American Society of Microbiology, 1985, p. 94.
McNulty, C. A. M., B. Crump, J. C. Gearty, M. Davis, I. A. Donovan, M. D. Manhart and R. Wise, "Successful Therapy of Campylobacter pyloridis Gastritis", Gastroenterology, May 1986, p. 1547.
McNulty, C. A. M., J. Dent and R. Wise, "Susceptibility of Clinical Isolates of Campylobacter pyloridis to 11 Antimicrobial Agents", Antimicrobial Agents and Chemotherapy, vol. 28, No. 6, (Dec. 1985), pp. 837-838.
Carlson, J. R., S. A. Thornton, H. L. DuPont, A. H. West and J. J. Mathewson, "Comparative in Vitro Activities of Ten Antimicrobial Agents Against Bacterial Enteropathogens", Antimicrobial Agents and Chemotherapy, vol. 24, No. 4, (Oct. 1983), pp. 509-513.
Vanhoff, R., B. Gordts, R. Dierickx, H. Coignau and J. P. Butzler, "Bacteriostatic and Bactericidal Activities of 24 Antimicrobial Agents Against Campylobacter fetus Subsp. Jejuni", Antimicrobial Agents and Chemotherapy, vol. 18, No. 7, (Jul. 1980), pp. 118-121.
Karmali, M. A., S. De Grandis and P. C. Fleming, "Antimicrobial Susceptibility of Campylobacter jejuni and Special Reference to Resistance Patterns of Canadian Isolates", Antimicrobial Agents and Chemotherapy, vol. 19, No. 4, (Apr. 1981), pp. 593-597.
Blaser, M. J., and L. B. Reller, "Campylobacter Enteritis", The New England Journal of Medicine, vol. 305, No. 24, (Dec. 10, 1981), pp. 1444-1452.
Warren, J. R., "Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastritis", The Lancet, vol. 1, (Jun. 4, 1983), p. 1273.
Marshall, B., "Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastritis", The Lancet, vol. 1, (Jun. 4, 1983), pp. 1273-1275.
McNulty, C. A. M., and D. M. Watson, "Spiral Bacteria of the Gastric Antrum", The Lancet, vol. 1, (May 12, 1984), pp. 1068-1069.
Marshall, B. J., and J. R. Warren, "Unidentified Curved Bacilli in the Stomach of Patients with Gastritis and Peptic Ulceration", The Lancet, vol. 1, (Jun. 16, 1984), pp. 1311-1315.
Langenberg, M. L., G. N. J. Tytgat, M. E. I. Schipper, P. J. G. M. Rietra and H. C. Zanen, "Campylobacter-Like Organisms in the Stomach of Patients and Healthy Individuals", The Lancet, vol. 1, (Jun. 16, 1984), p. 1348.
Burnett, R. A., J. A. H. Forrest, R. W. A. Girdwood and C. R. Fricker, "Campylobacter-Like Organisms in the Stomach of Patients and Healthy Individuals", The Lancet, vol. 1, (Jun. 16, 1984), p. 1349.
Marshall, B. J., D. B. McGechie, G. J. Francis and P. G. Utley, "Pyloric Campylobacter Serology", The Lancet, vol. 2, (Aug. 4, 1984), p. 281.
McLean, A. J., P. M. Harrison, L. L. Ioannides-Demos, A. J. Byrne, P. McCarthy and F. J. Dudley, "Microbes, Peptic Ulcer and Relapse Rates with Different Drugs", The Lancet, vol. 2, (Sep. 1, 1984), pp. 525-526.
Marshall, B. J., D. B. McGechie, P. A. Rogers and R. J. Glancy, "Pyloric Campylobacter Infection and Gastroduodenal Disease", The Medical Journal of Australia, vol. 142, (Apr. 15, 1985), pp. 439-444.
Zheng, Z. T., Z. Y. Wang, Y. X. Chu, Y. N. Li, Q. F. Li, S. R. Lin and Z. M. Xu, "Double-Blind Short-Term Trial of Furazolidone in Peptic Ulcer", The Lancet, vol. 1, (May 4, 1985), pp. 1048-1049.
McNulty, C. A. M., and R. Wise, "Rapid Diagnosis of Campylobacter-Associated Gastritis", The Lancet, vol. 1, (Jun. 22, 1985), pp. 1443-1444.
Flores, B. M., C. L. Fennell, K. K. Holmes and W. E. Stamm, "In Vitro Susceptibilites of Campylobacter-Like Organisms to Twenty Antimicrobial Agents", Antimicrobial Agents and Chemotherapy, vol. 28, No. 2, (Aug. 1985), pp. 188-191.
Jones, D. M., A. Curry and A. J. Fox, "An Ultrastructural Study of the Gastric Campylobacter-Like Organism `Campylobacter pyloridis`", Journal of General Microbiology, vol. 131, (1985), pp. 2335-2341.
Shirokova, K. I., R. M. Filimonov and L. V. Poliakova, "The Use of Metronidazole in Treatment of Patients with Ulcerative Disease", Klin. Med., (Mosk), vol. 59, No. 2, (Feb. 1981), pp. 48-50.
Zheng, Z. T., Z. Y. Wang, Y. X. Chu, Z. M. Xu, Z. X. Li, X. W. Dong and Z. J. Wang, "Treatment of Gastrointestinal Ulcer by Furazolidone", Chinese Journal of Digestion, vol. 2, (1982), pp. 131-133.
Lu, L., F. Zhou and J. Yu, "Effect of Furaxon and its Analogs on Gastrointestinal Propulsion in Mice", Beijing Yixueyuan Xuebao, vol. 15, No. 3, (1983), pp. 185-187.
Zheng, Z. T., T. Y. Wang, Y. S. Zhu, Y. Y. Lee, J. F. Lee, S. Z. Lin and G. M. Xu, "A Double-Blind Short-Term Clinical Trial of the Effect of Furazolidone on Peptic Ulcer", Chinese Journal of Internal Medicine, vol. 23, No. 4, (Apr. 1984), pp. 195-197.
He, B. E. and S. C. He, "Cytoprotection of Furazolidone in Restraint-Soakage Gastric Ulcers in Rats", Jinan Liyi Xuebao, vol. 4, (1984), pp. 55-59.
Zhang, S., J. Shao and Y. Yu, "Protective Effects of Furazolidone and Some Commonly Used Antiulcer Drugs on Several Gastric Ulcer Models in Rats", Yaoxue Xuebao, vol. 19, No. 1, (1984), pp. 5-11.

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